respiratory medicine Flashcards

1
Q

fine crackles causes

A

pulmonary oedema

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

exudative vs transudative pulmonary effusions

A

transudative - high pressure eg. HF, LV, CKD, cirrhosis, Pulmonary embolism
exudative - high protein & LDH eg. infection, malignancy,

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

end expiratory BILATERAL wheeze

A

asthma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

polyphonic inspiratory and expiratory (biphasic) wheeze

A

COPD

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

clubbing in COPD?

A

no clubbing in COPD

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

causes of stridor?

A

Croup
Epiglottitis
Post-extubation laryngeal edema
Foreign body aspiration

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

breathlessness score?

A

MRC dyspnoea scale

MRC grade 1 - SOB only on strenerous exercise
grade 2 - even when climbing slight hill
5 grades with different statements that patient says when they get breathless

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

causes of obstructive lung disease

A

Asthma, COPD, bronchiectasis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

causes of restrictive lung disease

A

pulmonary fibrosis, asbestos, sacroidosis, obesity, neuromuscular disorders, kyphosis, obesity, acute respiratory distress syndrome

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

spirometry obstructive vs restrictive

A

obstructive: FEV1 significantly reduced & FVC normal or slightly reduced —-> FEV1:FVC reduced
restrictive: FEV1 slightly reduced & FVC is significantly reduced –> FEV1:FVC increased or normal

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

investigations for obstructive sleep apnoea

A

ABG: compensated respiratory acidosis
Hypertension
Epworth sleepiness scale questionnaire
Multiple sleep latency test (MSLT) - time to fall asleep in dark room using EEG criteria
sleep studies (polysomnography) with pulse oximetry, EEG, thoraco-abdominal wall movement

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

COPD patient, pneumothorax 1.5 cm

A

aspirate +/- chest drain
sit up
high flow oxygen but keep an eye on sats
monitor for 24hrs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

COPD patient, pneumothorax 0.5cm

A

sit up
high flow high flow oxygen but keep an eye on sats
monitor for 24hrs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

cut offs pneumothorax for do nothing vs aspiration vs chest drain

A

primary

  • <2cm monitor and review
  • > 2cm aspirate –> chest drain

secondary
<1cm do nothing
1-2cm aspirate –> chest drain
>2cm chest drain

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

criteria for LTOT in COPD?

A

measure ABG on 2 occasions, 3 weeks apart on optimum medication
two ABGs pO2 < 7.3kPa
ABG pO2 7.3-8kPa + pulmonary HTN or peripheral oedema or secondary polycythemia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

COPD patient, pneumothorax 2.5cm

A

chest drain

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

which heart murmur can give you haemoptysis?

A

mitral stenosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

cardiac pulmonary oedema vs acute respiratory distress syndrome

A

pulmonary capillary wedge pressure is high then this is due to backlog into veins due to heart failure

ARDS can only be diagnosed in absence of heart failure

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Venturi mask in COPD

A

24/28% blue Venturi masks

Sats of 88-92%

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Steroid conc acute exacerbation of asthma or copd

A

In asthma, give 100mg IV hydrocortisone

In COPD, give 200mg IV hydrocortisone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Asthma reversibility cut off

A

FEV1 > 12% with SABA

22
Q

site of aspiration in tension pneumothorax

A

2nd ICS mid clavicular line

6th ICS anterior axillary line in safe triangle

23
Q

site of safe triangle

A
lateral border of pec major
anterior border of lattisimus dorsi
6th ICS (nipple) directly ABOVE the rib
24
Q

what way does the trachea/mediastinum deviate for different pathologies?

A

tension - away
lobal collapse - towards
pleural effusion - away

25
Q

causes of pneumothorax

A

spontaneous
secondary to chronic lung issues: COPD, asthma, Marfans, mechanical ventilation
trauma - rib fractures, central line insertion

26
Q

left lobe collapse on X ray

A
  1. sail sign/ triangle behind the heart + NB. lung field may actually seem normal
  2. aortic -knob sign – the aortic arch is very circular and prominent
  3. reduction of volume on left (can be subtle) + elevation of the left diaphgram!
27
Q

normal ABG values

A

pH 7.35 - 7.45
pCO2 35-45 mmHg
HCO3- 22-26
pO2 80-100 mmHg

28
Q

when do you do V/Q over CTPA for pulmonary embolism?

A

pregnancy
renal failure (can’t deal with contrast)
allergic to contrast

29
Q

where is bifurcation of trachea?

A

T5 to 7 (behind sternum)

30
Q

where is bifurcation of AORTA?

A

L4 just above the junction of the left and right common iliac veins.

31
Q

mx of massive PE

A

local guidelines
intra-arterial: urgent pulmonary angiography and perfusion of thrombolytic drugs into the pulmonary arteries to dissolve the thrombus

OR intravenous: thrombolysis can be done via peripheral IV if radiological expertise is not available or less severely comprised patients

surgical thrombectomy is done at cardiothoracic units

32
Q

examples of thrombolytics

CI to thrombolytic agent use

A

egs. streptokinase, urocinase, recombinant tissue plasminogen activator

CIs: BLEEDING

  • recent haemorrhage, trauma, surgery
  • suspected/known aortic dissection
  • suspected/known peptic ulcer disease
  • previous allergy
  • previous history of intracerebral haemorrhage event
  • severe HTN
33
Q

presenting CXR

A

Rotation - clavicles equidistant from spinous processes
Inspiration - 6 anterior ribs
Peneration - vertebrae (+ see anterior ribs, if over peneterated then will see mainly posterior ribs)
Exposure - can you see entire chest

34
Q

presentation of any imaging/ investigations

A

what is it? orientation eg. PA/AP

patient details
date and time taken
previous images
was the patient symptomatic?

35
Q

how does cystic fibrosis result in chronic renal failure

A

CF –> systemic amyloidosis

36
Q

Hilar enlargement causes

A

Bilateral -

  • infection: TB, HIV
  • inflammation: sarcoidosis, pneumonoconiosis, silicosis,
  • malignancy: (lymphoma, mets)
  • vascular: pulmonary hypertension (COPD, recurrent mets)

Unilateral/asymmetrical - malignancy, TB, pulmonary artery aneurysm

37
Q

TB diagnosis

A
  1. CXR
  2. sputum stain for acid fast bacilli
  3. sputum culture for TB - most specific and sensitive
    - 3 samples, 8 hrs, at least one in the morning
  4. NAAT (nucleic acid amplification test)
    - can use sputum sample or sample from bronchoscopy with broncholavage
    - quick diagnosis but not all centers have it
  5. bloods - low Hb (chronic disease), raised WCC, pancytopenia (disseminated infection)

tuberculin skin test is not so helpful

38
Q

what do you do if you have a patient with acid fast bacilli

A

TB until proven otherwise

  1. negative pressure side room (minimise transmission to other parts of hospital)
  2. tell hospital infection control team
  3. inform local Health Protection Consultant
39
Q

cause of bronchial breath sounds

A

pneumonia

expiratory lasts longer than inspiratory

40
Q

DDx multiple ill defined opacities in CXR

A
infection
- septic emboli
Inflammation
- rheumatoid arthritis
- granulomatosis with polyangitis 
malignancy
- pulmonary mets
vascular
- pulmonary infarcts (following PE, death of lung tissue)

NB. miliary TB gives much smaller lesions a few mm in diameter

41
Q

MX of mesothelioma

A

no effective treatments

installation of sclerosant substances (dehydrating the pleural cells) to prevent re-accumulation of pleural effusions resulting in breathlessness

typically mets to lungs, hilar, other pleura in the body

42
Q

Miliary shadowing CXR

A

Miliary - few mm blotches everywhere

Tuberculosis!!
Sarcoidosis
Mets
Extrinsic allergic alveolilitis
Occupational lung disease
43
Q

Mx of aspergilloma/ mycetoma

A
  1. IV antifungals

2. surgical resection

44
Q

which lung malignancy causes a horner’s syndrome?

what can it result in?

A

superior sulcus/ apical lung carcinoma aka pancoast tumour

tumours can invade and compress surrounding structures resulting in Pancoast syndrome

invasion of sympathetic chain = Horners
invasion of brachial plexus = shoulder/arm pain
compession of spinal cord
recurrent laryngeal nerve invasion = hoarse voice

45
Q

how does aspergillus species affect the lung?

A
  1. asthma (type 1 hypersensitivity)
  2. allergic bronchopulmonary aspergillosis (type 1 & 3 hypersensitivity) - recurrent asthma and bronchial damage and bronchiectasis
  3. extrinsic allergic alveolitis - reccurent dyspnoea and dry cough and ultimately fibrosis
  4. mycetoma (aspergilloma) - fungus bal forming in a pre-existing lung cavity
  5. invasive aspergillosis in the immunosuppressed with high mortality
46
Q

DDx cavitating mass on chest radiograph

A

infection

  • s.aureus
  • klebsiella
  • mycetoma (aspergillus)
  • TB

wegener’s granulomatosis (granulomatosis with polyangitis)

carcinoma of the bronchus, SCC metastasis

pulmonary infarct

47
Q

diagnosis of aspergillus disease

A

serum preciptins is best

aspergillus skin test is positive in 30% of cases

48
Q

Mx of aspergilloma/ mycetoma

A
  1. IV antifungals

2. surgical resection

49
Q

most common histological subtype of lung cancer

A

adenocarcinoma 40%

50
Q

causes of superior vena cava syndrome

A

malignancy - bronchal ca, lymphoma in hilum

thrombosis secondary to pacing wirses or central venous catheters

51
Q

mx of superior vena cava syndrome

A
  1. oxygen, head elevate
  2. steroids, diuretics to relieve laryngeal/ cerebral oedema
  3. surgical bypass or SVC stenting
52
Q

ddx widespread opacity

A
pulmonary oedema (bat wing/ hilar)
non-cardiogenic pulmonary oedema

aspiration
pulmonary haemorrhage
pneumocystis pneumonia (ground glass)