Respiratory Infections In CF

Question 1

what are the symptoms of chronic progressive bronchiectasis?

Answer 1

Chronic sputum production

Increasing exertional dyspnoea (may lead to type 1 or type 2 resp failure)

Question 2

What is the treatment for chronic progressive bronchiectasis?

Answer 2

Oxygen
Nocturnal non-invasive ventilation
Symptomatic relief I.e. bronchodilators

Question 3

Chronic progressive bronchiectasis causes progressive ……

Answer 3

Airflow obstruction

Question 4

In patients with CF, survival is related to ?

Answer 4

FEV1

Question 5

When is transplantation recommended for CF patients?

Answer 5

When FEV1 < 30% predicted
And:
- hypoxia at rest
- hypercapnia 
- recurrent worsening sepsis

Question 6

What is the treatment for CF patients with infection caused by staph aureus?

Answer 6

Oral —> beta lactam + aminoglycoside

Question 7

What is the treatment for infection in CF patient caused by pseudomonas?

Answer 7

IV beta lactam + aminoglycoside

Question 8

How long are the drugs given in CF patients with infection?

Answer 8

2 weeks

Question 9

What is the treatment given for CF patient with an infection caused by pseudomonas aerguinosa?

Answer 9

Oral ciproflaxin + clarithromycin

Question 10

What CF patients is a pneumothorax more commonly found in?

Answer 10

Older males

Question 11

When does pseudomonas become resistant to antibiotics?

Answer 11

After it forms a biofilm

Question 12

What organisms are contra indicators for transplantation?

Answer 12

Genamovar III strain of burkholderia cepacia

Mycobacterium abcessus

Question 13

What organisms are commonly acquired from other CF patients?

Answer 13

Pseudomonas aeruginosa

Bulkohlderia cepacia

Question 14

Some CF patients infected by bulkholderia can develop what syndrome and what can this cause?

Answer 14

Capacia syndrome which can cause a rapid deterioration in lung function reducing life expectancy by 20 years

Question 15

what pathogen is responsible for croup?

Answer 15

Parainfluenza virus