Respiratory Failure Flashcards
What is hypoxaemia?
Lack of O2 in arterial blood
PaO2 < 8 kPa
What is hypercarbia?
Too much CO2 in arterial blood
PaCO2 > 7 kPa
What is type 1 respiratory failure?
- Oxygenation failure
- Hypoxaemia with normal/low PaCO2
- Affects part of lung - remaining able to excrete CO2
What is type 2 respiratory failure?
- Ventilatory failure
- Hypoxaemia + Hypercarbia
- Affects whole lung - inadequate ventilation = CO2 accumulation
What are the causes of type 2 RF?
- Depression of respiratory centre
- Respiratory muscle weakness
- Chest wall deformity
- Severe lung disease
What are the signs of low O2?
Confusion, restlessness, cyanosis, tachypnoea (rapid breathing)
What are the signs of high CO2?
Drowsiness, confusion, headache, agitation, bounding pulse, asterixis
How is type 2 RF treated?
- Oxygen - LT 16 hours/day
- Poor prognosis
How is type 1 RF treated?
- Ventilation + non-invasive ventilation
- Even poorer prognosis
- Overnight ventilation
What is normal blood pH?
7.35-7.45
What pH is alkalaemia?
pH > 7.45
What pH is acidaemia?
pH < 7.35
How are changes in CO2 controlled?
Changes in ventilation
How are changes in HCO3 controlled?
Renal absorption/excretion
What is normal oxygen saturation?
> 94 %