Respiratory Drugs Flashcards

1
Q

Epinephrine Class

A

Sympathetic Agonist

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2
Q

MOA of Epinephrine

A

Acts directly on α and β adrenergic receptors with a preference to β receptors. This results in increased hear rate, cardiac contractile force, systemic vascular resistence, increased blood pressure, bronchodilation and vasoconstriction.

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3
Q

Onset of Epinephrine

A

3-10 minutes IM

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4
Q

Peak effects of Epinephrine

A

20 minutes IM

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5
Q

Duration of Epinephrine

A

20-30 minutes IM

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6
Q

Indications for Epinephrine

A

Bronchial asthma, COPD exacerbation, allergic reaction, anaphylaxis.

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7
Q

Contraindications for Epinephrine

A

Cardiovascular disease, hypertension.

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8
Q

When should IV Epi 1/10mg be used in respiratory emergencies?

A

In patients with profound anaphylaxis with hypotension and shock. These patients will be peripherally vasoconstricted and absorption of IM med will be delayed.

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9
Q

Side effects of Epinephrine

A

Palpitations, anxiety, tremulousness, headache, dizziness, N&V, increased myocardial oxygen demand and subsequent myocardial ischemia.

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10
Q

Dosage of IM Epinephrine

A
  1. 3-0.5 mg adult IM

0. 01 mg/kg peds IM

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11
Q

Class of Albuterol

A

Sympathetic agonist

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12
Q

MOA of Albuterol

A

Albuterol is a selective sympathomimetic for β2 adrenergic receptors. This causes prompt bronchodilation.

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13
Q

Onset of Albuterol

A

5-15 minutes inhaled

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14
Q

Peak effects of Albuterol

A

1-1.5 hours

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15
Q

Duration of Albuterol

A

3-6 hours

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16
Q

Half life of Albuterol

A

3 hours

17
Q

Indications for Albuterol

A

Bronchial asthma and reversible bronchospasm associated with chronic bronchitis and emphysema.

18
Q

Contraindications for Albuterol

A

Hypersensitivity.

19
Q

Side effects of Albuterol

A

Palpitations, anxiety, dizziness, headache, nervousness,t tremors, hypertension, arrhythmias, chest pain, N&V.

20
Q

Interactions of Albuterol

A

May cause increased unpleasant side effects when used with other sympathetic agonists. Effects may be blunted by β-blockers.

21
Q

Interactions of Epinephrine

A

Effects of Epinephrine may be intensified in patients taking antidepressants.

22
Q

Dosage of Albuterol

A

2.5 mg small volume nebulizer