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3rd Year > Respiratory drugs > Flashcards

Respiratory drugs Flashcards

1
Q

What sort of drug is salbutamol?

A

B2 agonist

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2
Q

What is salbutamol used for?

A

Asthma
COPD
Premature labour

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3
Q

Common side effects of salbutamol?

A

Tremor

Tachycardia

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4
Q

If combined with Corticosteriods, loop/thiazide diuretics or theophylline what does salbutamol increase the risk of?

A

Hypokalaemia

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5
Q

How does salbutamol work?

A

Stimulates B2 receptors in the airways generating intracellular cAMP
Decreases intracellular calcium = bronchodilation
Prevents mast cell degranulation

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6
Q

Contraindication for salbutamol?

A 
Hyperthyroidism
Cardio disease
Arrhythmias
Hypertension
Be cautious in diabetes as rink of ketoacidosis
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7
Q

What do anticholinergic drugs do?

A

Inhibit parasympathetic nerve impulses

Inhibit the involuntary movements of smooth muscles present in gastrointestinal tract, urinary tract and lungs.

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8
Q

What sort of drug is ipratropium bromide? What does it do?

A

Antimuscarinic agent. Affects the receptors at the bronchi, it inhibits mucous secretion.

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9
Q

Give an example of a common corticosteroid

A

Prednisolone

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10
Q

What effect are corticosteroids used for?

A

Anti-inflammatory effect

immunosuppresive effect

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11
Q

Indications for prednisolone?

A

Suppression of allergic/inflammatory disease
IBD
Asthma
Rheumatoid disease
Immunosuppression (leukaemia, transplant)

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12
Q

Common side effects of Corticosteroids?

A 
Bruising
Hirsutism
Moon-face
Hypertension
Weight gain/oedema
Glucose intolerance
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13
Q

What drugs can interact to decrease the effect of prednisolone?

A

Phenytoin

Rifampicin

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14
Q

What are patients at risk of if you withdraw corticosteroids too quickly after long-term treatment?

A

Acute adrenal crisis

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15
Q

Contra-indications for corticosteroid use?

A 
Systemic infection
Hypersensitivity
Osteoporosis
Glaucoma
Admin of live vaccines
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16
Q

Indications for O2 therapy?

A 
Resuscitation (up to 100%)
High concentration (up to 60%) in acute hypoxic events
Low concentration (up to 28%) in respiratory disease with C02 retention
17
Q

Give examples of acute hypoxic events?

A 
MI
Asthma
Poisoning
Pneumonia
PE

3rd Year (18 decks)

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