Respiratory drugs Flashcards by Hannah Wilkinson

Q

What are core drug classes of respiratory drugs?

A

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Q

Where are B2 adrenoceptors?

A

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Q

What nerve supply do muscarinic cholinergic receptors receive?

A

parasympathetic

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Q

What is the definition of asthma?

A

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Q

What is the definition of COPD?

A

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Q

What is the aim of pharmacological management of asthma and COPD?

A

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Q

are inhalers efficient?

A

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Q

A

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Q

What factors determine drug reposition in the lungs?

A

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Q

Are larger particles distribute in the lungs centrally or distally?

A

Centrally.
Smaller particles are distributed more distally.

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Q

Which bronchodilators are used for asthma and COPD?

A

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Q

If you give nebulised salbutamol, how much O2 or air should you give with asthma or COPD?

A

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Q

How long are the effects of salbutamol?

A

onset within 10 mins.
lasts 3-5hrs

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Q

What are the side effects of salbutamol?

A

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Q

How does ipratropium bromide work?

A

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Q

Which drug is a SAMA?

A

Ipratropium bromide

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Q

Which drugs are LAMAs?

A

Tiotropium
Aclidinium

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Q

What is the MOA of tiotropium?

A

LAMA
Inhibits M3 receptors in the smooth muscle
Results in bronchodilatation of airways and reduced mucus production

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Q

How often is tiotropium given?

A

once daily, long acting (24hrs)

Q

When would tiotropium be indicated?

A

Stable COPD - symptoms despite SABA
Chronic asthma - Not improving despite ICS/LABA

Q

What are the side effects of SAMAs and LAMAs?

A

Q

What are the different types of corticosteroids?

A

Q

What are the advantages and disadvantages of systemic and inhaled corticosteroids?

A

Q

What are the side effects of ICS?

A

What are the side effects of oral side effects?

Which inhalers are combined ICS/LABA?

What are three types of inhaler devices?

How long should you wait to do a second puff with a pMDI?

1 minute

How do DPI's work?

How do nebulisers work?

What are the different types of methylxanthines?

How are methylxanthines metabolised?

What drug class is montelukast?

What is the MOA of montelukast?

When is montelukast indicated?

When are monoclonal antibodies indicated?

What are mucolytic agents? How do they work?

which document should be created and given to patients with asthma?

Personalised asthma self-management plan

How is acute asthma assessed?

How is acute asthma managed?

What is the general management of COPD?

The use of inhaled therapy for COPD is dependent on what factors?

What is the definition of a COPD exacerbation?

How are COPD exacerbations managed?