Respiratory drugs

Question 1

What are core drug classes of respiratory drugs?

Answer 1

Question 2

Where are B2 adrenoceptors?

Answer 2

Question 3

What nerve supply do muscarinic cholinergic receptors receive?

Answer 3

parasympathetic

Question 4

What is the definition of asthma?

Answer 4

Question 5

What is the definition of COPD?

Answer 5

Question 6

What is the aim of pharmacological management of asthma and COPD?

Answer 6

Question 7

are inhalers efficient?

Answer 7

Question 9

What factors determine drug reposition in the lungs?

Answer 9

Question 10

Are larger particles distribute in the lungs centrally or distally?

Answer 10

Centrally.
Smaller particles are distributed more distally.

Question 11

Which bronchodilators are used for asthma and COPD?

Answer 11

Question 12

If you give nebulised salbutamol, how much O2 or air should you give with asthma or COPD?

Answer 12

Question 13

How long are the effects of salbutamol?

Answer 13

onset within 10 mins.
lasts 3-5hrs

Question 14

What are the side effects of salbutamol?

Answer 14

Question 15

How does ipratropium bromide work?

Answer 15

Question 16

Which drug is a SAMA?

Answer 16

Ipratropium bromide

Question 17

Which drugs are LAMAs?

Answer 17

Tiotropium
Aclidinium

Question 18

What is the MOA of tiotropium?

Answer 18

LAMA
Inhibits M3 receptors in the smooth muscle
Results in bronchodilatation of airways and reduced mucus production

Question 19

How often is tiotropium given?

Answer 19

once daily, long acting (24hrs)

Question 20

When would tiotropium be indicated?

Answer 20

Stable COPD - symptoms despite SABA
Chronic asthma - Not improving despite ICS/LABA

Question 21

What are the side effects of SAMAs and LAMAs?

Answer 21

Question 22

What are the different types of corticosteroids?

Answer 22

Question 23

What are the advantages and disadvantages of systemic and inhaled corticosteroids?

Answer 23

Question 24

What are the side effects of ICS?

Answer 24

Question 25

What are the side effects of oral side effects?

Answer 25

Question 26

Which inhalers are combined ICS/LABA?

Answer 26

Question 27

What are three types of inhaler devices?

Answer 27

Question 28

How long should you wait to do a second puff with a pMDI?

Answer 28

1 minute

Question 29

How do DPI's work?

Answer 29

Question 30

How do nebulisers work?

Answer 30

Question 31

What are the different types of methylxanthines?

Answer 31

Question 32

How are methylxanthines metabolised?

Answer 32

Question 33

What drug class is montelukast?

Answer 33

Question 34

What is the MOA of montelukast?

Answer 34

Question 35

When is montelukast indicated?

Answer 35

Question 36

When are monoclonal antibodies indicated?

Answer 36

Question 37

What are mucolytic agents? How do they work?

Answer 37

Question 38

which document should be created and given to patients with asthma?

Answer 38

Personalised asthma self-management plan

Question 39

How is acute asthma assessed?

Answer 39

Question 40

How is acute asthma managed?

Answer 40

Question 41

What is the general management of COPD?

Answer 41

Question 42

The use of inhaled therapy for COPD is dependent on what factors?

Answer 42

Question 43

What is the definition of a COPD exacerbation?

Answer 43

Question 44

How are COPD exacerbations managed?

Answer 44