Respiratory drugs Flashcards by Hannah Wilkinson

Q

What are core drug classes of respiratory drugs?

A

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Q

Where are B2 adrenoceptors?

A

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Q

What nerve supply do muscarinic cholinergic receptors receive?

A

parasympathetic

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Q

What is the definition of asthma?

A

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Q

What is the definition of COPD?

A

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Q

What is the aim of pharmacological management of asthma and COPD?

A

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Q

are inhalers efficient?

A

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Q

A

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Q

What factors determine drug reposition in the lungs?

A

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Q

Are larger particles distribute in the lungs centrally or distally?

A

Centrally.
Smaller particles are distributed more distally.

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Q

Which bronchodilators are used for asthma and COPD?

A

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Q

If you give nebulised salbutamol, how much O2 or air should you give with asthma or COPD?

A

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Q

How long are the effects of salbutamol?

A

onset within 10 mins.
lasts 3-5hrs

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Q

What are the side effects of salbutamol?

A

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Q

How does ipratropium bromide work?

A

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Q

Which drug is a SAMA?

A

Ipratropium bromide

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Q

Which drugs are LAMAs?

A

Tiotropium
Aclidinium

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Q

What is the MOA of tiotropium?

A

LAMA
Inhibits M3 receptors in the smooth muscle
Results in bronchodilatation of airways and reduced mucus production

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Q

How often is tiotropium given?

A

once daily, long acting (24hrs)

Q

When would tiotropium be indicated?

A

Stable COPD - symptoms despite SABA
Chronic asthma - Not improving despite ICS/LABA

Q

What are the side effects of SAMAs and LAMAs?

A

Q

What are the different types of corticosteroids?

A

Q

What are the advantages and disadvantages of systemic and inhaled corticosteroids?

A

Q

What are the side effects of ICS?

A

Q

What are the side effects of oral side effects?

A

Q

Which inhalers are combined ICS/LABA?

A

Q

What are three types of inhaler devices?

A

Q

How long should you wait to do a second puff with a pMDI?

A

1 minute

Q

How do DPI’s work?

A

Q

How do nebulisers work?

A

Q

What are the different types of methylxanthines?

A

Q

How are methylxanthines metabolised?

A

Q

What drug class is montelukast?

A

Q

What is the MOA of montelukast?

A

Q

When is montelukast indicated?

A

Q

When are monoclonal antibodies indicated?

A

Q

What are mucolytic agents? How do they work?

A

Q

which document should be created and given to patients with asthma?

A

Personalised asthma self-management plan

Q

How is acute asthma assessed?

A

Q

How is acute asthma managed?

A

Q

What is the general management of COPD?

A

Q

The use of inhaled therapy for COPD is dependent on what factors?

A

Q

What is the definition of a COPD exacerbation?

A

Q

How are COPD exacerbations managed?

A

Q

A