Drugs used in arrhythmias Flashcards by Hannah Wilkinson

Q

MOA of Lidocaine (Lignocaine)?

A

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Q

How do class I anti-arrhythmic drugs affect the action potential?

A

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Q

When do class I agents bind most avidly?

A

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Q

What are the differences between class Ia, Ib and Ic?

A

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Q

What are the indications for flecainide?

A

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Q

What are the side effects of flecainide?

A

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Q

What type of solubility does Amiodarone have?

A

Lipid soluble so very large volume of distribution

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Q

What is the MOA of Amiodarone?

A

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Q

What are the side effects of Amiodarone?

A

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Q

What do you monitor when someone is on Amiodarone and how frequently?

A

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Q

What are the indications for Amiodarone?

A

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Q

What class is Dronedarone and when is it used?

A

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Q

What do these adrenoceptors cause?

A

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Q

What is the molecular action of beta receptors?

A

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Q

What is the MOA of calcium channel blockers?

A

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Q

Which drug has a larger effect on reducing heart rate?

A

Q

Which drug has a larger effect on reducing cardiac contractility?

A

Q

Which drug has a larger vasodilatory effect?

A

Q

What are the indications for verapamil/diltiazem?

A

Q

What is the MOA of adenosine?

A

Q

What is adenosine broken down into?

A

Q

Who is adenosine CI in?

A

Asthmatic patients - causes bronchoconstriction

Q

A

Q

A

When is adenosine used?

What is the MOA of atropine?

What does acetylcholine activate?

When is atropine ineffective?

When is isoprenaline used?

What does isoprenaline increase?

What is the funny channel?

What is the MOA of Ivabradine?

What is the MOA of digoxin?

Antidote for digoxin?

Digibind

What ecg effect do you get from digoxin?

Class I and III act on cardiac electrical tissue so it can prolong what?

QT and QRS intervals They are pro-arrhythmic