Drugs used in arrhythmias Flashcards

1
Q

MOA of Lidocaine (Lignocaine)?

A
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2
Q

How do class I anti-arrhythmic drugs affect the action potential?

A
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3
Q

When do class I agents bind most avidly?

A
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4
Q

What are the differences between class Ia, Ib and Ic?

A
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5
Q

What are the indications for flecainide?

A
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6
Q

What are the side effects of flecainide?

A
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7
Q

What type of solubility does Amiodarone have?

A

Lipid soluble so very large volume of distribution

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8
Q

What is the MOA of Amiodarone?

A
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9
Q

What are the side effects of Amiodarone?

A
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10
Q

What do you monitor when someone is on Amiodarone and how frequently?

A
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11
Q

What are the indications for Amiodarone?

A
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12
Q

What class is Dronedarone and when is it used?

A
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13
Q

What do these adrenoceptors cause?

A
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14
Q

What is the molecular action of beta receptors?

A
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15
Q

What is the MOA of calcium channel blockers?

A
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16
Q

Which drug has a larger effect on reducing heart rate?

17
Q

Which drug has a larger effect on reducing cardiac contractility?

18
Q

Which drug has a larger vasodilatory effect?

19
Q

What are the indications for verapamil/diltiazem?

20
Q

What is the MOA of adenosine?

21
Q

What is adenosine broken down into?

22
Q

Who is adenosine CI in?

A

Asthmatic patients - causes bronchoconstriction

25
Q

When is adenosine used?

26
Q

What is the MOA of atropine?

27
Q

What does acetylcholine activate?

28
Q

When is atropine ineffective?

29
Q

When is isoprenaline used?

30
Q

What does isoprenaline increase?

31
Q

What is the funny channel?

32
Q

What is the MOA of Ivabradine?

33
Q

What is the MOA of digoxin?

34
Q

Antidote for digoxin?

35
Q

What ecg effect do you get from digoxin?

37
Q

Class I and III act on cardiac electrical tissue so it can prolong what?

A

QT and QRS intervals
They are pro-arrhythmic