Drugs used in arrhythmias Flashcards

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1
Q

MOA of Lidocaine (Lignocaine)?

A
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2
Q

How do class I anti-arrhythmic drugs affect the action potential?

A
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3
Q

When do class I agents bind most avidly?

A
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4
Q

What are the differences between class Ia, Ib and Ic?

A
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5
Q

What are the indications for flecainide?

A
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6
Q

What are the side effects of flecainide?

A
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7
Q

What type of solubility does Amiodarone have?

A

Lipid soluble so very large volume of distribution

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8
Q

What is the MOA of Amiodarone?

A
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9
Q

What are the side effects of Amiodarone?

A
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10
Q

What do you monitor when someone is on Amiodarone and how frequently?

A
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11
Q

What are the indications for Amiodarone?

A
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12
Q

What class is Dronedarone and when is it used?

A
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13
Q

What do these adrenoceptors cause?

A
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14
Q

What is the molecular action of beta receptors?

A
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15
Q

What is the MOA of calcium channel blockers?

A
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16
Q

Which drug has a larger effect on reducing heart rate?

A
17
Q

Which drug has a larger effect on reducing cardiac contractility?

A
18
Q

Which drug has a larger vasodilatory effect?

A
19
Q

What are the indications for verapamil/diltiazem?

A
20
Q

What is the MOA of adenosine?

A
21
Q

What is adenosine broken down into?

A
22
Q

Who is adenosine CI in?

A

Asthmatic patients - causes bronchoconstriction

23
Q
A
24
Q
A
25
Q

When is adenosine used?

A
26
Q

What is the MOA of atropine?

A
27
Q

What does acetylcholine activate?

A
28
Q

When is atropine ineffective?

A
29
Q

When is isoprenaline used?

A
30
Q

What does isoprenaline increase?

A
31
Q

What is the funny channel?

A
32
Q

What is the MOA of Ivabradine?

A
33
Q

What is the MOA of digoxin?

A
34
Q

Antidote for digoxin?

A

Digibind

35
Q

What ecg effect do you get from digoxin?

A
36
Q
A
37
Q

Class I and III act on cardiac electrical tissue so it can prolong what?

A

QT and QRS intervals
They are pro-arrhythmic

38
Q
A