RESPIRATORY & CARDIOVASCULAR SYSTEM Flashcards
- Which of the following are correct regarding Adult respiratory distress syndrome (ARDS):
(a) CXR is usually normal in the first 24 h.
(b) The lung is uniformly abnormal on CT.
(c) Has 50% mortality.
(d) The most common CT abnormality in survivors in a reticular pattern.
(e) Bronchial dilatation is seen frequently on CT.
Answers:
(a) Correct
(b) Not correct
(c) Correct
(d) Correct
(e) Correct
Explanation:
Lung involvement is heterogeneous with a gradient density. Dependent lung is more densely opacified than nondependent
lung
- Which of the following are correct regarding thoracic trauma:
(a) A normal erect CXR virtually exclude acute thoracic aortic injury.
(b) Uncomplicated pulmonary contusion on CXR begins to resolve after at least 7 days.
(c) Air bronchograms are a common CXR feature of pulmonary contusion.
(d) Pulmonary lacerations appear as ovoid lucent areas.
(e) Main bronchial injuries are more common than tracheal injuries
Answers:
(a) Correct
(b) Not correct
(c) Not correct
(d) Correct
(e) Correct
Explanation:
Air bronchograms are usually absent in pulmonary contusions as result of blood filling the airways.
Uncomplicated pulmonary contusions begin to resolve after 48-72 hrs. Complete resolution is seen usually by 10-14
days.
- Which of the following are correct about thoracic aorta:
(a) Stanford type B dissection affects the ascending aorta.
(b) Penetrating aortic ulcers are frequently multiple.
(c) Mycotic aneurysms are usually fusiform in configuration.
(d) Penetrating aortic ulcers usually progress to dissection.
(e) Type A dissection is more common than Type B.
Answers:
(a) Not correct
(b) Correct
(c) Not correct
(d) Not correct
(e) Correct
Explanation:
Dissection affecting ascending aorta is classified as Stanford type A and accounts for 75% of aortic dissection. Acute
type A is a surgical emergency to avoid fatal complications. Stanford type B dissection affects the descending aorta.
Mycotic aneurysms are usually saccular and may grow rapidly.
Penetrating atherosclerotic ulcers usually progress to aneurysmal dilatation
- Regarding diagnosis of pulmonary embolism (PE):
(a) A negative D-dimer test reliably excludes PE in patients with low clinical probability.
(b) A positive D-dimer test is highly specific for PE.
(c) A normal isotope lung scan reliably excludes PE.
(d) Patients with a good quality negative CTPA do not require further investigation or treatment for PE.
(e) Digital subtraction pulmonary angiography is the investigation of choice for patients with suspected massive
PE.
Answers:
(a) Correct
(b) Not correct
(c) Correct
(d) Correct
(e) Not correct
Explanation:
A positive D-dimer test has a poor specificity for PE, especially in hospitalized patients.
CTPA or echocardiography is the investigations of choice in case of massive PE
- Which of the following are correct about pulmonary sarcoidosis:
(a) Normal CXR excludes the diagnosis.
(b) The large airways are involved in 4-5% of cases.
(c) Subcarinal lymph nodes are characteristically spared.
(d) Fibrosis occurs predominantly in the lower zones.
(e) Pleural effusion is common CXR.
Answers:
(a) Not correct
(b) Correct
(c) Not correct
(d) Not correct
(e) Not correct
Explanation:
Between 5% to 15% of patients have a normal CXR when first examined.
Pleural effusion is a rare finding (2%).
All mediastinal lymphnodes can be affected in sarcoidosis. On CT 50% of cases show enlarged subcarinal
lymphnodes.
Middle and upper zone fibrosis is characteristic.
- Which of the following are correct regarding cardiac myxoma:
(a) Is the most common primary cardiac tumour.
(b) 80-90% of patients have arrhythmias.
(c) 70-80% are found in the right atrium.
(d) Invasion of the myocardium is seen in >50% at presentation.
(e) Have a low signal on gradient-echo MRI sequences
Answers:
(a) Correct
(b) Not correct
(c) Not correct
(d) Not correct
(e) Correct
Explanation:
Approximately 75% of myxomas are located in left atrium, 20% in right atrium and rare cases are found in ventricles.
The classical clinical triad of obstructive cardiac symptoms, embolic phenomena and constitutional symptoms has
been described and majority of the patients have atleast one of these symptoms at presentation.
Cardiac myxomas are endocardial based masses that do not infiltrate the underlying tissues.
- Which of the following are correct regarding pulmonary disease in AIDS patients:
(a) Lymphocytic interstitial pneumonia usually progresses to lymphoma in children.
(b) Bilateral perihilar infiltrates on CXR are diagnostic of Pneumocystis Carinii pneumonia.
(c) The presence of Cytomegalovirus in bronchoalveolar lavage fluid indicates active infection.
(d) Lymphadenopathy is seen in <5% of cases of Kaposi’s sarcoma.
(e) Thick-walled cavities are a common HRCT finding of invasive pulmonary aspergillosis
Answers:
(a) Not correct
(b) Not correct
(c) Not correct
(d) Not correct
(e) Correct
Explanation:
Bilateral perihilar infiltrates are a non-specific findings seen in other opportunistic infections as well like CMVand
Kaposi’s sarcoma. On HRCT, PCP is most commonly seen as bilateral, symmetric, patchy or confluent ground glass
opacity. Less common findings on CXR and HRCT include focal areas of consolidation, mass lesions, multiple lung
nodules, pleural fluid, pneumothorax, cavitation, lymphadenopathy and occasional nodal calcification.
CMV is the most common viral pathogen to cause morbidity and mortality in patients with AIDS. The HRCT findings
are heterogeneous and include bilateral ground glass opacities, multiple nodules or mass like areas of consolidations
and patchy bilateral consolidation.
Pulmonary KS occurs in 18% to 50% of patients with known cutaneous KS and can affect the lung parenchyma,
pleural or tracheobronchial tree. Bilateral perihilar pulmonary infiltrates is the most common finding. Other common
findings include intralobular septal thickening, lymphadenopathy and pleural effusion.
Lymphocytic interstitial pneumonia is a lymphoproliferative disorder seen with increased frequency in mainly
children affected by AIDS. It is mostly benign and regresses spontaneously or with treatment.
- Which of the following are correct regarding HRCT features of pulmonary alveolar proteinosis (PAP):
(a) Usually shows a lower zone distribution.
(b) Pleural effusion is common at presentation.
(c) Lymphadenopathy is a common feature.
(d) Regions of emphysema are commonly observed.
(e) Crazy paving pattern is a specific feature.
Answers:
(a) Correct
(b) Not correct
(c) Not correct
(d) Not correct
(e) Not correct
Explanation:
Pleural effusion is rare in untreated PAP.
Lymphadenopathy is uncommon.
Crazy paving pattern though suggestive of PAP, is also seen in ARDS, acute interstitial pneumonia and drug induced
pneumonias.
- Which of the following are correct regarding extrinsic allergic alveolitis (EAA):
(a) A normal CXR excludes the diagnosis.
(b) Smoking is a risk factor.
(c) The upper zones are typically involved in acute EAA.
(d) Ground-glass opacity is a characteristic HRCT finding.
(e) Bronchiectasis is seen on HRCT in chronic EAA.
Answers:
(a) Not correct
(b) Not correct
(c) Not correct
(d) Correct
(e) Correct
Explanation:
CXRs are generally normal in patients with mild symptoms and in some cases with severe symptoms.
Smokers are protected from EAA also called hypersensitivity pneumonitis. The most common forms are farmer’s lung
and bird fancier’s lung.
Typically mid to lower zones are affected with sparing of costophrenic angles. Presentation is like pulmonary oedema
with bilateral areas of increased opacity that may be heterogeneous or homogeneous.
- Which of the following are correct regarding Langerhans’ cell histiocytosis.
(a) Primarily affects cigarette smokers.
(b) Predominantly affects the lung bases.
(c) Most patients are asymptomatic.
(d) Nodular lesions frequently cavitate.
(e) Lung volumes are reduced.
Answers:
(a) Correct
(b) Not correct
(c) Not correct
(d) Correct
(e) Not correct
Explanation:
LCH mostly involves upper and mid zones with relative sparing of lung bases and characteristic appearance of
bilateral nodular and reticulo-nodular areas.
Most patients are symptomatic with non-productive cough and/or dyspnoea.
Lung volumes are characteristically normal or increased.
- Which of the following are correct regarding bronchopulmonary sequestration:
(a) Intralobar sequestration (IS) typically presents in the neonatal period.
(b) Extralobar sequestration (ES) is more common than intralobar sequestration.
(c) The main blood supply is form bronchial arteries.
(d) Most commonly affect the lower lobes.
(e) Can cause recurrent chest infection in adults.
Answers:
(a) Not correct
(b) Not correct
(c) Not correct
(d) Correct
(e) Correct
Explanation:
Bronchopulmonary sequestration is a non-functioning sequestered lung segment which has no communication with the
tracheobronchial tree and has a systemic blood supply. Supply is commonly from a separate branch from the aorta and
sometimes from upper abdominal vessels or coronary arteries.
IS is more common (80%) and ES is found in (20%). IS typically presents in adulthood and is often an incidental
finding.
- When a solitary pulmonary nodule is seen on computed tomography (CT), which of the following
radiological features suggested it is benign?
(a) Amorphous calcification within the nodule.
(b) Air bronchograms within the nodule.
(c) CT attenuation of – 10 Hounsfield units (HU).
(d) Lobulated outline of the nodule.
(e) Enhancement of the nodule by less than 15 HU following intravenous contrast.
Answers:
(a) Not correct
(b) Not correct
(c) Correct
(d) Not correct
(e) Correct
Explanation:
Popcorn type calcification indicated benignity and is typical of hamartoma. Amorphous calcification is seen in upto
7% of lung carcinomas.
Air bronchograms may be seen within a tumour mainly bronchoalveolar carcinoma.
Lobulated outline and corona radiate on CT are typical of carcinoma.
- Which of the following are true regarding malignant mesothelioma?
(a) Selective involvement of the parietal pleura is typical.
(b) Pleural effusions are common.
(c) Chest wall invasion occurs in 12% of cases at presentation.
(d) Circumferential pleural thickening is typical.
(e) It is a cause of hypertrophic osteoarthropathy.
Answers:
(a) Not correct
(b) Correct
(c) Correct
(d) Correct
(e) Correct
Explanation:
Nodular thickening of both parietal and visceral pleura is usual in mesothelioma.
- Which of the following are true regarding round pneumonia?
(a) It is most commonly associated with Klebsiella infection.
(b) It occurs most commonly in the second and third decades of life.
(c) It is more common in the upper lobes.
(d) It frequently progresses to cavitation.
(e) It is a feature of Q-fever infection.
Answers:
(a) Not correct
(b) Not correct
(c) Not correct
(d) Not correct
(e) Correct
Explanation:
It is most commonly associated with Streptococcus pneumonia.
Round pneumonia occurs most frequently in children within first decade of life.
It is usually seen in lower lobes, often abutting pleural space.
Round pneumonia evolves rapidly over a few days into segmental consolidation (sometimes with air bronchograms).
Cavitation is unusual.
- Which of the following are true regarding silicosis?
(a) It predominantly affects the lower lobes in acute silicoproteinosis.
(b) Emphysema is associated with the development of progressive massive fibrosis.
(c) It mimics sarcoidosis on high resolution computed tomography (HRCT).
(d) It is a more frequent cause of nodal egg-shell calcification on radiograph than coal miner’s pneumoconiosis.
(e) Impairment of the lung function test correlates best with the profusion of nodules.
Answers:
(a) Not correct
(b) Correct
(c) Correct
(d) Correct
(e) Not correct
Explanation:
Acute silicoproteinosis has mid and upper zone predominance occurs from intense exposure to silica dust resulting in
alveolar exudates.
Impairment of the lung function test correlates best with the degree of emphysematous change. Nodular perfusion is a
weaker independent correlate.
- When a mass-like lesion is seen on CT, which of the following findings support the diagnosis of rounded
atelectasis.
(a) An anteromedial location of the mass.
(b) An acute angle with the pleural margins.
(c) Localized crowding of the pulmonary vasculature.
(d) Adjacent pleural thickening.
(e) Absence of enhancement following intravenous contrast
Answers:
(a) Not correct
(b) Correct
(c) Correct
(d) Correct
(e) Not correct
Explanation:
Round atelectasis is usually seen in posterior or basal region of lower lobes and appears as a well-defined oval or
round mass in subpleural location.
On Ct the mass shows uniform post intravenous contrast enhancement
- Which of the following are true regarding usual interstitial pneumonitis (UIP)?
(a) It is more common in females than males.
(b) It occurs most frequently in the sixth decade of life.
(c) It is the most common cause of cryptogenic fibrosing alveolitis.
(d) Areas of ground glass attenuation on HRCT in the absence of parenchymal distortion indicate reversibility.
(e) A confident diagnosis cannot be made on HRCT without lung biopsy.
Answers:
(a) Not correct
(b) Correct
(c) Correct
(d) Correct
(e) Not correct
Explanation:
UIP has no gender predilection. On HRCT temporal heterogeneity is characteristic of UIP and it refers to different
areas of lung demonstrating different stages of inflammation and fibrosis at the same time. This helps to make
confident diagnosis in majority of the cases.
- Which of the following are true regarding cryptogenic organising pneumonia (COP)?
(a) The disease is rarely symptomatic.
(b) An obstructive pattern of lung function impairment is typical.
(c) Pleural effusions are common.
(d) Radiographic clearing occurs following steroid treatment.
(e) Bilateral basal peripheral consolidation is a common radiographic finding
Answers:
(a) Not correct
(b) Correct
(c) Not correct
(d) Correct
(e) Correct
Explanation:
50% of the patients are symptomatic presenting with fever, cough, breathlessness and malaise with peak incidence in
5th and 6th decades of life. COP is also known as BOOP (bronchiolitis obliterans organizing pneumonia) or
bronchiolitis obliterans with intramural polyps.
Pleural effusion is uncommon (5% cases).
- Which of the following are true regarding blunt pulmonary trauma?
(a) Pulmonary contusions show radiographic resolution in 48 hours.
(b) Bronchial rupture is always accompanied by pneumothorax.
(c) Traumatic diaphragmatic rupture is more common on the left side.
(d) A normal chest radiograph has a good negative predictive value for aortic rupture.
(e) Aortic rupture most commonly occurs at the aortic root.
Answers:
(a) Correct
(b) Not correct
(c) Correct
(d) Correct
(e) Not correct
Explanations:
Bronchial rupture is frequently (70%), not always associated with pneumothorax. The falling lung sign is typical and
refers to displacement of lung to the dependant position.
Aortic rupture is the most common at ductus arteriosus level.
- Which of the following are correct regarding fibromuscular dysplasia (FMD):
(a) Is more common in males.
(b) Usually affects the intimal layer.
(c) Renal artery FMD is bilateral in 5% of cases.
(d) Can occur in veins.
(e) May present with a transient ischaemic attack
Answers:
(a) Not correct
(b) Not correct
(c) Not correct
(d) Correct
(e) Correct
Explanation:
FMD is more common in females and presents between 15 to 50 yrs.
Medial fibroplasia is more common form of FMD with characteristic ‘strings of beads’ appearance. Intimal
fibroplasia occurs in 10% of cases and adventitial hyperplasia is the rarest form.
Renal artery FMD is bilateral in approximately 30% of cases