GENITO-URINARY SYSTEM Flashcards
- Which of the following are correct of multicystic dysplastic kidneys?
(a) Antenatal ultrasound reveals a paraspinal mass with multiple communicating cysts.
(b) Approximately 30% of contralateral kidneys are abnormal.
(c) It is more common in infants of diabetic mothers.
(d) Upto 20% of cases have residual renal function in the affected kidney on scintigraphy.
(e) Nephrectomy is usually required, as it cannot be differentiated from cystic Wilms tumour.
Answers:
(a) Not correct
(b) Correct
(c) Correct
(d) Correct
(e) Not correct
Explanation:
Antenatal ultrasound shows multiple non-communicating cysts of variable size. Serial ultrasound scans of multicystic
dysplastic kidney show renal involution. Nephrectomy is required if it fails to involute or if there is uncontrolled
hypertension.
Multicystic dysplastic kidney is the second most common cause of neonatal abdominal mass (first is hydronephrosis).
- Regarding medullary sponge kidney, which of the following are correct?
(a) The cystic areas in the medulla do not communicate with the collecting ducts.
(b) The changes are unilateral in 25% of cases.
(c) It is a feature of Meckel-Gruber syndrome.
(d) Medullary nephrocalcinosis is visible radiographically in 10% of cases.
(e) There is an association with Ehlers-Danlos syndrome.
Answers:
(a) Not correct
(b) Correct
(c) Not correct
(d) Not correct
(e) Correct
Explanation:
Medullary sponge kidney is a common sporadic condition affecting young to middle aged adults. There is dysplastic
cystic dilatation of papillary and medullary collecting ducts.
Meckel- Gruber syndrome is an autosomal recessive syndrome comprising of multicystic dysplastic kidneys, occipital
encephalocele and polydactyly.
Medullary nephrocalcinosis is visible radiographically in 40% - 80%.
- Concerning renal papillary necrosis, which of the following are correct?
(a) Necrosis involves the overlying cortex in 10% of cases.
(b) It may result from aspirin use.
(c) A single papilla is affected in approximately 15% of cases.
(d) It is associated with a higher incidence of renal tract squamous cell carcinoma.
(e) Medullary sponge kidney is a cause.
Answers:
(a) Not correct
(b) Correct
(c) Correct
(d) Correct
(e) Not correct
Explanation:
Cortex is not involved in renal papillary necrosis. It involves pyramids and medullary papilla. Medullary sponge
kidney causes renal papillary calculi not necrosis.
- Which of the following are correct regarding renal cell carcinoma?
(a) About 75% of tumours less than 3cm in size are hyperechoic on ultrasonography.
(b) Von Hippel-Lindau syndrome is risk factor.
(c) Calcification and cystic change occur in the minority of cases.
(d) About 30% of tumours are hypovascular on angiography.
(e) The lungs are the most common site for metastatic spread.
Answers:
(a) Correct
(b) Correct
(c) Correct
(d) Not correct
(e) Correct
Explanation:
5% of RCC are hypovascular on angiography. Tumours cause neovascularity. Renal vein or IVC extension of tumour
is also seen on angiography.
- Concerning ureterocoeles, which of the following are correct?
(a) About 80% of ectopic ureterocoeles occur in duplicated systems.
(b) In children, a pseudoureterocoele most commonly results from an impacted stone.
(c) They can be indistinguishable from bladder diverticula during voiding.
(d) A simple ureterocoele never occurs in an ectopic ureter.
(e) A single simple ureterocoele can cause bladder outlet obstruction
Answers:
(a) Correct
(b) Correct
(c) Correct
(d) Correct
(e) Correct
Explanation:
Ureterocoele is a congenital dilatation of distal most portion of ureter. In minority of cases it is an isolated finding and
seen in adults. On IVP it shows ‘cobra head’ sign.
Complications include obstructive cystic renal dysplasia
- Which of the following are correct regarding retroperitoneal fibrosis?
(a) When the ureters are involved, there is typically only mild pyelocalyectasis.
(b) The fibrotic plaque usually originates around the aortic bifurcation.
(c) On CT, the aorta is typically enveloped and anteriorly displaced by a fibrotic mass.
(d) An increase in signal intensity on T2 weighted imaging indicates a good response to steroid treatment.
(e) It is associated with primary sclerosing cholangitis.
Answers:
(a) Correct
(b) Correct
(c) Not correct
(d) Not correct
(e) Correct
Explanation:
On CT, the aorta is engulfed by the fibrotic mass but not displaced. Displacement is seen in malignancy.
Steroid treatment causes a decrease in signal intensity on T2WI indicating a good response
- In prune belly syndrome, which of the following are correct?
(a) The condition is more common in females.
(b) The inheritance is autosomal recessive.
(c) It is characterised by markedly distended and obstructed ureters.
(d) There is an association with Hirschsprung’s disease.
(e) Death occurs within 1 year of birth in the majority of cases
Answers:
(a) Not correct
(b) Not correct
(c) Not correct
(d) Correct
(e) Not correct
Explanation:
Prune belly syndrome is a sporadic nonhereditary condition, exclusively affecting males. It is characterized by triad
of absent anterior abdominal wall muscles, non-obstructed megaureters and cryptorchidism (due to bladder
distension).
In 20% cases death occurs in first month of life and another 30% within 2 yrs of life. Mild cases survive into
adulthood.
- Regarding testicular ultrasound, which of the following are correct?
(a) Absent testicular blood flow on colour Doppler imaging is pathognomonic of testicular torsion.
(b) There is an association between testicular microlithiasis and Klinefelter’s syndrome.
(c) Testicular cysts are seen in upto 10% of testicular ultrasound studies.
(d) The epididymis is typically enlarged, hypervascular and hyperechoic when inflamed.
(e) The normal epididymis is slightly hypoechoic to the normal testis.
Answers:
(a) Not correct
(b) Correct
(c) Correct
(d) Not correct
(e) Not correct
Explanation:
In paediatric patients intratesticular flow can be difficult to demonstrate on colour Doppler. Power Doppler may be
helpful in such cases.
When inflamed epididymis is typically enlarged, hypervascular and hypoechoic. Orchitis is seen in 20% cases and
shows similar appearance.
The normal epididymis is isoechoic to slightly hyperechoic to normal testis.
- Which of the following are correct regarding screening tests for breast cancer in the general population?
(a) Screening mammography has been shown to reduce mortality from breast cancer.
(b) Screening using ultrasound has been shown to reduced breast cancer mortality in patients less than 35 years
old.
(c) Two views of the breast are obtained for all screening assessments.
(d) Cancers showing casting linear calcifications on mammography are associated with a poorer prognosis.
(e) In the UK, mammographic screening is currently advocated for women aged over 40 years.
Answers:
(a) Correct
(b) Not correct
(c) Not correct
(d) Correct
(e) Not correct
Explanation:
Two views of each breast are taken as baseline, but single view is taken as follow up. However two views are
recommended as follow up as it increases lesion detection.
Ultrasound currently has no role as a screening tool in any age group.
In UK, screening is available for patients from 50-65 yrs.
- Which of the following are correct regarding invasive breast cancers?
(a) Rim calcification is frequently seen in medullary carcinoma.
(b) There is an association between tubular carcinoma and radial scar.
(c) The most common invasive cancer in the male breast in invasive lobular carcinoma.
(d) Colloid carcinoma has a worse prognosis than invasive ductal carcinoma.
(e) The likelihood of axillary spread of invasive ductal carcinoma depends on the size of the tumour.
Answers:
(a) Not correct
(b) Correct
(c) Not correct
(d) Not correct
(e) Correct
Explanation:
Medullary carcinoma presents as well defined mass which may show lobulated margins or halo sign. Calcification is
not a feature.
The most common invasive cancer in male breast is invasive ductal carcinoma.
Colloid carcinoma is seen in older age group (over 60 yrs) and has a good prognosis as tumour is slow growing.
- Which of the following are correct regarding calcification detected on mammography?
(a) Skin calcifications typically have central lucent centres.
(b) Mild of calcium has a typical appearance on the cranio-caudal view.
(c) “Bilateral scattered punctate calcifications are probably benign.
(d) Rim calcification is a feature of fat necrosis.
(e) Sutural calcification are usually linear in appearance.
Answers:
(a) Correct
(b) Not correct
(c) Correct
(d) Correct
(e) Correct
Explanation:
Milk of calcium appears amorphous and ill-defined on cranial caudal view.
On medial-lateral oblique view it is typically sharply defined, semilunar or crescent shaped and upwardly concave.
- Which of the following statements are correct regarding fibroadenomas?
(a) They occur bilaterally in 25% of cases.
(b) The incidence is higher in women receiving hormone replacement therapy.
(c) The typically demonstrate posterior acoustic shadowing on ultrasonography.
(d) Internal septations are typical on gadolinium-enhanced MRI.
(e) They are clinically palpable in the majority of cases.
Answers:
(a) Not correct
(b) Correct
(c) Not correct
(d) Correct
(e) Correct
Explanation:
Fibroadenomas are multiple in 10%- 20% of cases but are found bilaterally in only 4 % of cases.
They are well circumscribed masses with homogenous internal echoes but variable posterior acoustic pattern.
- Which of the following are correct regarding sclerosing adenosis?
(a) It has an association with lobular carcinoma.
(b) It is a condition with high premalignant potential.
(c) Biopsy is required to make a definitive diagnosis.
(d) It presents with a palpable mass in the majority of cases.
(e) It commonly presents as focal or diffuse calcification.
Answers:
(a) Correct
(b) Not correct
(c) Correct
(d) Not correct
(e) Correct
Explanation:
Sclerosing adenosis is only mildly associated (2.5 folds) with increase in risk of infiltrating breast cancer. The
condition in itself is non-malignant.
It is frequently detected only on mammography, though may present as a palpable mass.
- Regarding ultrasonography in the first trimester of pregnancy, which of the following are correct?
(a) Gestational sac volume is the most accurate estimate of gestational age in the first 8 weeks of pregnancy.
(b) The diameter of the yolk sac should not be more than 5mm.
(c) The yolk sac is normally identified before the foetal pole.
(d) A normal intrauterine gestational sac and foetal pole exclude an ectopic pregnancy.
(e) Cardiac pulsation becomes visible at the beginning of the eighth postmenstrual week.
Answers:
(a) Not correct
(b) Correct
(c) Correct
(d) Not correct
(e) Not correct
Explanation:
Once the fetus can be identified (5-6wks) then crown to rump length (CRL) is the most accurate measurement.
The biparietal diameter becomes the most accurate towards end of the first trimester.
Cardiac pulsation is visualized as soon as a fetal pole is visualized i.e. at 6 weeks postmenstrual week on TAS.
A coexistent intrauterine and ectopic pregnancy (heterotopic pregnancy) is extremely rare (1 in 30000 pregnancy).
- Which of the following statements are correct?
(a) An empty gestational sac with a mean sac diameter of 10mm and an elevated â human chorionic gonadotrophin
(HCG) is consistent with a blighted ovum.
(b) Beta-HCG levels double every week in the first 8 weeks of pregnancy.
(c) An absent intrauterine pregnancy on ultrasonography and â-HCG levels between 1000 and 2000 IU is highly
suspicious of an ectopic pregnancy.
(d) Vaginal bleeding is not usually associated with an ectopic pregnancy.
(e) The risk of a second ectopic pregnancy is 10%.
Answers:
(a) Correct
(b) Not correct
(c) Correct
(d) Not correct
(e) Not correct
Explanation:
Beta-HCG levels double every 2-3 days in the first 8 weeks of pregnancy.
Vaginal bleeding is seen in 75%-85% cases of ectopic pregnancies. The risk of second ectopic pregnancy is 25%.
- An axial ultrasonographic section through the foetal head measurement of the biparietal diameter (BPD)
should include which of the following?
(a) The third ventricle.
(b) The thalami.
(c) The cavum septum pellucidum.
(d) A continuous echogenic midline.
(e) The cerebellum.
Answers:
(a) Correct
(b) Correct
(c) Correct
(d) Not correct
(e) Not correct
Explanation:
BPD is used for estimating the gestational age after 12 weeks. Its accuracy declines after 28 weeks after which it is
combined with second measurement like femur length.
- Regarding uterine leiomyomas, which of the following are correct?
(a) Simple leiomyomas can metastasise.
(b) Cystic degeneration occurs in 30% of cases.
(c) Red degeneration is associated with the contraceptive pill.
(d) Calcification is usually peripheral.
(e) They are typically of low T2 signal relative to the surrounding myometrium.
(a) Correct
(b) Not correct
(c) Correct
(d) Not correct
(e) Correct
Explanation:
In leiomyomas (fibroids) cystic degeneration is rare, seen only in 4 % cases.
Calcification is seen associated with red degeneration, and is typically scattered and amorphous marking the site of
hyaline degeneration.
- Which of the following statements are correct?
(a) The risk of an ectopic pregnancy is higher in patients with a unicornuate uterus.
(b) Nabothian cysts occur in the posterolateral wall of the lower third of the vagina.
(c) The uterus is derived from the paired mullerian ducts.
(d) A unicornuate uterus is rarely associated with other anomalies.
(e) Gartner’s duct cysts are typically located anterolateral to the upper two thirds of the vagina.
Answers:
(a) Correct
(b) Not correct
(c) Correct
(d) Not correct
(e) Correct
Explanation:
Bartholin’s cyst occurs in posterolateral wall of lower third of vagina.
Mucous retention within endocervical glands is known as nabothian cyst and can be seen in any wall of cervix.
40% cases of unicornuate uterus is associated with renal and ureteric anomalies.
- Which of the following statements are correct?
(a) Haematocolpos refers to a uterine cavity distended with blood.
(b) After puberty, the most common cause of haematocolpos is vaginal atresia.
(c) A fluid collection within the endometrial cavity of a neonate is abnormal.
(d) Congenital haematometrocolpos is usually associated with other anomalies.
(e) Haematometra is a cause of ureteric obstruction
Answers:
(a) Not correct
(b) Not correct
(c) Not correct
(d) Correct
(e) Correct
Explanation:
Hematocolpos refers to vagina distended with blood and hematometra refers to uterine cavity distended with blood.
An imperforate hymen is the most common cause of hematocolpos.
Approximately 25% of neonates have a fluid collection within the endometrial cavity, thus a normal finding.