Pediatric Flashcards
- Regarding hypertrophic pyloric stenosis, which of the following are correct:
(a) It is frequently diagnosed in premature infants.
(b) Males and females are equally affected.
(c) The peak incidence is between 2 and 6 months of age.
(d) It is associated with gastric pneumatosis.
(e) An elongated pyloric canal measuring 14 mm on ultrasound supports the diagnosis.
Answers:
(a) Not correct
(b) Not correct
(c) Not correct
(d) Correct
(e) Not correct
Explanation:
Hypertrophic pyloric stenosis is typically seen in first born males with peak incidence between 2 and 6 weeks of age.
It is rarely seen in premature infants.
To make a diagnosis on ultrasound the pyloric canal length should be 17mm, pyloric wall thickness atleast 3 mm and
transverse diameter of pylorus atleast 13 mm.
- Regarding infantile polycystic kidney disease, which of the following are correct?
(a) The most common age of presentation is between 2 and 5 years of age.
(b) It is inherited as an autosomal dominant condition.
(c) Severe infantile polycystic disease is associated with severe hepatic fibrosis.
(d) Is typically reveals a striated nephrogram on the delayed excretory urogram.
(e) Infantile polycystic kidneys are echopoor on ultrasound
Answers:
(a) Not correct
(b) Not correct
(c) Not correct
(d) Correct
(e) Not correct
Explanation:
Infantile polycystic kidney disease is inherited in an autosomal recessive pattern with antenatal form being the most
common type. This type presents in utero and progresses to renal failure and pulmonary hypoplasia (Potter sequence)
with majority of patients dying within 24 hrs of life.
The milder forms are neonatal, infantile and juvenile presenting in the first few years of life. They are associated with
more severe hepatic fibrosis and less severity of renal disease.
The affected kidneys are replaced my multiple small elongated cysts representing dilated tubules and collecting ducts.
The cysts are too small to be delineated on ultrasound, thus producing an echogenic pattern due to multiple interfaces.
There is poor corticomedullary differentiation.
Adult type polycystic disease shows autosomal dominant inheritance with defects on chromosome 16 and 4.
- In childhood which of the following are correct regarding non-Hodgkin’s lymphoma?
(a) Non-Hodgkin’s lymphoma is more common than Hodgkin’s disease in young children.
(b) Splenic involvement occurs in more than 70 % of cases atpresentation.
(c) Pulmonary involvement is more common in Hodgkin’s disease.
(d) Central nervous system disease at presentation indicates a poor prognosis.
(e) There is a higher incidence of extra-nodal disease in childhood non-Hodgkin’s lymphoma than when it occurs
in adults.
Answers:
(a) Correct
(b) Not correct
(c) Correct
(d) Correct
(e) Correct
Explanation:
Abdominal involvement in non-Hodgkin’s usually presents with a mass typically at ileocaecal region or
intussusception causing obstruction.
Splenic involvement is seen in less than 40% of cases at presentation
- Which of the following statements are correct?
(a) The normal thymus in a child is hypoechoic relative to the liver.
(b) The thymus is highly vascular on color Doppler ultrasound.
(c) The thymus arises from the third and fourth branchial pouches.
(d) Teratomas comprise the most common anterior mediastinal mass in childhood.
(e) Thymolipomas are common causes of thymic enlargement in childhood.
Answers:
(a) Correct
(b) Not correct
(c) Correct
(d) Not correct
(e) Not correct
Explanation:
Normal thymus is hypovascular on color Doppler.
Thymic hyperplasia is the most common anterior mediastinal mass in childhood. It may be secondary to
hyperthyroidism, myasthenia gravis and rebound growth following illness or stress.
Thymomas and Thymolipomas are extremely rare in childhood. Neoplastic involvement is usually secondary to
infiltration by leukemia or lymphoma.
- Which of the following statements are correct?
(a) The ‘H’ type traheo-oesophageal fistula is the most common.
(b) Duodenal atresia usually presents with bilious vomiting.
(c) Duplication cysts of the gastrointestinal tract are most common in the ileal region.
(d) Duodenal duplication cysts are located on the convex border of the duodenum.
(e) Duodenal atresia is associated with malrotation of the small bowel.
Answers:
(a) Not correct
(b) Correct
(c) Correct
(d) Not correct
(e) Correct
Explanation:
The H type trachea-esophageal fistula is seen only in 10% cases. Upper esophageal atresia with a fistula between
lower esophagus and trachea is the most common type (85%).
Duodenal duplication cysts are usually situated along the concave border where they may cause duodenal obstruction,
biliary obstruction or pancreatitis.
- Which of the following statements are correct?
(a) Vesico-ureteric reflux usually occurs into the lower pole moiety of a complete ureteral duplication
(b) Ectopic ureterocoeles in duplex kidneys are more common in boy than girls.
(c) An ectopic ureteral insertion may present with daytime incontinence in a girl.
(d) Horseshoe kidneys are associated with a higher incidence of duplicated kidneys.
(e) Ectopic ureteral insertion in boys in always supra-sphincteric.
Answers:
(a) Correct
(b) Not correct
(c) Correct
(d) Correct
(e) Correct
Explanation:
Ureterocoeles which are related to the upper pole moiety of a duplex kidney occur 8 times more frequently in girls
than boys.
Ureterocoeles related to non-duplicated system show an equal gender incidence.
- Which of the following statements are correct?
(a) Ewing’s tumors rarely arise within flat bones.
(b) Giant cell tumors of bone are most commonly seen in the 5-15 years age group.
(c) Parosteal osteosarcomas have a peak in the 10-20 years age group.
(d) Eosinophilic granuloma usually involves one bone only.
(e) Ewing’s tumors often demonstrate calcification on CT.
Answers:
(a) Not correct
(b) Not correct
(c) Not correct
(d) Correct
(e) Not correct
Explanation:
About 60% of Ewing tumors arise in long bones, most common site is metadiaphysis of femur. About 40% arise in flat
bones especially in pelvis, particularly in patients over 20 years age. Calcification is rare in Ewing’s tumor of bone.
It typically presents with an onion skin periosteal reaction on radiograph.
Majority of giant cell tumors occur in patients following fusion of the epiphysis. Thus usually occur after 18-20 years
of age. They have a narrow zone of transition and usually abut the articular margin.
Parosteal osteosarcomas occur in an older age group than the periosteal type with 50% occurring after 30 years of
age.
- Regarding hepatoblastomas, which of the following are correct?
(a) Alpha-fetoprotein levels are not elevated.
(b) Presentation is usually after 4 years of age.
(c) Following intravenous contrast enhanced CT, hepatoblastomas are hypodense relative to the surrounding liver.
(d) Calcification is rarely seen.
(e) MRI characteristics of hepatocellular carcinomas and hepatoblastomas are similar.
Answers:
(a) Not correct
(b) Not correct
(c) Correct
(d) Not correct
(e) Correct
Explanation:
Hepatoblastomas typically present as an abdominal mass in an asymptomatic child under 2 yrs of age. Hepatocellular
carcinoma presents over 4 yrs of age.
Both hepatoblastomas and hepatocellular carcinoma cause elevated alpha-fetoprotein levels. Hepatoblastomas are
associated with hemihypertrophy and Beckwith-Wiedemann syndrome.
Calcification is present in 50% cases of hepatoblastomas.
- Regarding Eosinophilic granuloma, which of the following are correct?
(a) Bone lesions are usually solitary
(b) The mandible is rarely involved
(c) Vertebral pedicels are typically affected
(d) The cranial vault is rarely involved
(e) A periosteal reaction is not seen on plain film.
Answers:
(a) Correct
(b) Not correct
(c) Not correct
(d) Not correct
(e) Not correct
Explanation:
EG typically involves the vertebral body, most commonly the thoracic spine, causing vertebra plana.
The skull is the most frequent site of involvement. Typically , there is round or oval lucency within the skull vault with
beveled edges.
It often involves the mandible causing ‘floating tooth ‘ appearance.
A periosteal reaction is not usually seen however it is not unusual in axial skeleton.
- Regarding wormian bones, which of the following are correct?
(a) They typically involve the coronal suture
(b) They are a normal finding up to 18 months of age.
(c) They are a feature of Down’s syndrome
(d) They are seen in sickle cell anaemia
(e) They are a feature of rickets
Answers:
(a) Not correct
(b) Not correct
(c) Correct
(d) Not correct
(e) Correct
Explanation:
Wormian bones are a normal finding upto 6-12 months of age.
They typically involve the lambdoid and posterior Sagittal sutures, extending around the posterior fontanelle.
Sickle cell and other types of anemia cause ‘hair on end’ appearance of cranial vault.
- Which of the following are correct of non-accidental injury (NAI):
- Cerebral injury from shaking is most common over 2 years of age
- Diaphyseal fracture are more common than metaphyseal fractures
- Multiple rib fracture are highly suspicious of NAI
- Spiral fracture of the tibia is highly suspicious
- Inter hemispheric subdural hematoma is an atypical finding
Answers:
1. Not correct
2. Correct
3. Correct
4. Not correct
5. Not correct
Explanation:
Cerebral injury from shaking is common below 2 years of age.
Spiral fractures of tibia occur usually secondary to trivial twisting injuries.
Inter hemispheric subdural hematoma is highly suspicious of NAI.
- Which of the following are correct regarding paediatric intussusception:
(a) Accounts for over 75 % of paediatric intestinal obstruction
(b) Plain films are typically abnormal
(c) Typically occurs between 4-8 years of age
(d) A lead point is identified in over 50 % of cases
(e) Pneumoperitoneum is a contraindication to air reduction
Answers:
(a) Correct
(b) Not correct
(c) Not correct
(d) Not correct
(e) Correct
Explanation:
In intussusception plain films can be normal in 50% cases with highest incidence between 3 months and 4 years of
age. In children 95 % intussusception are idiopathic with no lead point.
- Which of the following are correct regarding radiological features of achondroplasia
(a) Dilatation of the lateral cerebral ventricles
(b) Decreased interpedicular distance caudally within the spine
(c) Short fibs
(d) Anterior vertebral scalloping
(e) Relative shortening of fibula
Answers:
(a) Correct
(b) Correct
(c) Correct
(d) Not correct
(e) Not correct
Explanation:
Posterior vertebral scalloping and relative lengthening of fibula are seen in achondroplasia
- Which of the following are correct regarding slipped upper femoral epiphysis
(a) Is seen typically between 4-8 years of age.
(b) The line of Klein should intersect the normal femoral head.
(c) Is bilateral in one third of cases.
(d) The epiphysis slips postero-medially.
(e) Subchondral lucency is an early sig
Answers:
(a) Not correct
(b) Correct
(c) Correct
(d) Correct
(e) Not correct
Explanation:
It is seen usually between 8-17 years of age.
Subchondral lucency is an early sign of Perthe’s disease
- The following are CNS features of tuberous sclerosis.
(a) Presentation is usually with seizures.
(b) Subependymal nodules are most common in the occipital horn of the lateral ventricles.
(c) Pilocytic astrocytoma is a complication.
(d) Cortical tubers are most prominent on T1W MRI.
(e) Calcification may be seen in upto 50 % on skull X-ray.
Answers:
(a) Correct
(b) Not correct
(c) Not correct
(d) Not correct
(e) Correct
Explanation:
In tuberous sclerosis subependymal nodules are most common along ventricular surface of caudate nucleus, with
cortical tubers which are most prominent on T2W and FLAIR.
Giant cell astrocytoma is a complication