Respiratory Antibiotics Flashcards
What is the difference between level I and level III evidence and which is better support for medication use?
Level I: evidence obtained from at least one properly designed randomized controlled trial.
Level III: opinions of respected authorities, based on clinical experience, descriptive studies, or reports of expert committees.
-level I evidence is better support for use of a drug
What is the best class (and name 3 meds in that class) that has level I evidence for use in pneumonia caused by Strep pneumo when the patient has no risk factors.
Macrolides
- Azithromycin
- Clarithromycin
- Erythromycin
Which drug classes have Level I evidence to treat community acquired pneumonia for a patient in the hospital but NOT in the ICU?
Fluoroquinolones-monotherapy
Beta-Lactams and Macrolides - combo therapy
Which drug class has level I evidence for use against community acquired pneumonia patients that are in the ICU?
Respiratory Fluoroquinolones
Moxi-, Gemi-, Levo-
Name 2 drugs used initially for acute sinusitis.
Amoxicillin
TMP-SMX
Name 5 monotherapy or combo therapy treatments for chronic sinusitis.
- Clindamycin
- Cefazolin/metronidazole
- Cefuroxime/metronidazole
- Clarithromycin
- Fluroquinolones
Name one oral and one IM antibiotic used for Strep pyogenes pharyngitis.
Penicillin V: oral
Penicillin G Benzathine: IM
-oral erythromycin if penicillin allergies exist
Name 3 treatments for patients with COPD that get an infection.
- TMP-SMX
- Azithromycin or Clarithromycin
- Doxycycline
Name 3 drugs used to treat pneumonia caused by penicillin resistant strep pneumo.
- Doxycycline
- Clindamycin
- Levofloxacin
Name 2 antibiotics used to treat pneumonia caused by legionella.
- Fluoroquinolones
2. Azithromycin
Name 4 antibiotics used to treat CAP in the elderly.
- Loracarbef
- Cefuroxime axetil
- Cefpodoxime
- Ceftriaxone
Name 3 antibiotics used against nosocomial pneumonia caused by MRSA.
- Vanco
- Linezolid
- Tigecycline
