Respiratory Anatomy Flashcards

1
Q

External respiration

A

Oxygen is absorbed from atmosphere into blood within pulmonary capillaries
Carbon dioxide secreted

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2
Q

Internal respiration

A

Exchange of gases between blood in systemic capillaries

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3
Q

Cellular respiration

A

Individual cells gain energy by breaking down molecules in mitochondria, consuming oxygen and generating carbon dioxide

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4
Q

Pulmonary ventilation

A

Bulk movement of air into and out of lungs

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5
Q

Ventilatory pump

A

Rib cage + associated muscles + diaphragm

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6
Q

Conducting part of respiratory system

A

Series of cavities and thick walled tubes which conduct air between the nose and the lungs
Nasal cavities + Pharynx + Larynx + Trachea + Bronchi + Bronchioles

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7
Q

Respiratory part of respiratory system

A

Tiny thin walled airways where gases are exchanged between air and blood
Respiratory bronchioles + Alveolar ducts + Alveolar sacs + Alveoli

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8
Q

Gas exchange location

A

Respiratory part of the respiratory system

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9
Q

Surface area of alveoli

A

75m2 (3/4 tennis court)

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10
Q

Upper respiratory tract

A

Nasal cavity to larynx

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11
Q

Lower respiratory tract

A

Trachea to bronchus to bronchioles to alveoli

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12
Q

Filtration location

A

Vibrissae (nasal hairs)

Mucociliary escalator

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13
Q

Warming location

A

Capillary network in nasal cavity underneath epithelium

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14
Q

Humidifying location

A

Nasal cavity covered in mucus membrane

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15
Q

Conchae

A

Bony projections that increase surface area of the mucus membrane in the nasal cavity and mix and slow down inhaled air

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16
Q

Air pathway from nose to trachea

A
Nose to nasopharynx
Nasopharynx to oropharynx
Oropharynx to laryngopharynx
Laryngopharynx to glottis
Glottis to trachae
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17
Q

Food pathway from mouth to oesophagus

A
Mouth to soft palate
Soft palate closes nasopharynx
Soft palate to oropharynx
Oropharynx to laryngopharynx
Epiglottis closes glottis
Oesophagus forced open
Laryngopharynx to oesophagus
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18
Q

Number of respiratory generations

19
Q

Conducting zone structures

A
Trachea
Main stem bronchi
Lobar bronchi
Segmental bronchi
Smaller bronchi
Bronchioles
Terminal bronchioles
20
Q

Respiratory zone structures

A

Respiratory bronchioles
Alveolar ducts
Alveolar sacs

21
Q

Lobes in lobar bronchi

A

3 lobes on the right

2 lobes on the left

22
Q

Describe the trachea

A

12cm long tube as thick as a thumb
Supported by incomplete C shaped rings of cartilage
Free ends of cartilage connected by smooth trachealis muscle
Lined with ciliated pseudostratified columnar epithelium
Cilia transport mucus sheet up towards nasopharynx
Anterior to oesophagus

23
Q

Describe the bronchus wall

A
Pseudostratified ciliated columnar epithelium and goblet cells lined with mucus
Smooth muscle
Mucus glands
Cartilage plates
Alveolus
24
Q

2 sources of mucus

A

Goblet cells and mucus glands

25
Describe the bronchiole wall
Simple ciliated columnar epithelium and club cells lined with watery secretion Smooth muscle Alveolus
26
Role of smooth muscle
Controls air flow by constriction and relaxation
27
Pathological cause of asthma
Over-constriction of smooth muscle in the bronchi and bronchioles restricting air flow and requiring bronchodilators to relax
28
Role of cartilage plates
Keep bronchi open - cartilage plates are not prone to collapse Bronchi more rigid than bronchioles because of presence of cartilage plates
29
Club cells
Found between epithelial cells in bronchiole walls and secrete a non-mucus watery secretion to keep cells hydrated and air moist
30
Goblet cells
Found between epithelial cells in bronchus walls and secrete mucus
31
Cells in alveolar walls
``` Red blood cells (in pulmonary capillary) Endothelial cells (in pulmonary capillary) Squamous pneumocytes (type I cells) Alveolar macrophages Surfactant cells (type II cells) ```
32
Role of surfactant
Liquid lining reduces the work of breathing by reducing surface tension in alveoli and stopping alveoli completely collapsing
33
Role of surfactant cells
To secrete surfactant
34
Role of squamous pneumocytes
Very thin trails of cytoplasm in each cell surrounding an area of an alveoli which minimises diffusion distance for gas exchange
35
Role of alveolar macrophages
Act as normal macrophages to engulf pathogens and foreign particles Last line of defence if air is contaminated
36
Describe the diffusion barrier in alveoli
Squamous pneumocyte adjacent to alveolar air space Capillary endothelium adjacent to blood plasma Basement membranes of squamous pneumocytes and capillary endothelium fused to reduce diffusion distance
37
Primary bronchi
Right and left main stem bronchi supplying each lung
38
Secondary bronchi
Lobar bronchi supplying lobes (3 on the right and 2 on the left)
39
Tertiary bronchi
Segmental bronchi supplying segments of the lung (10 on the right and 8 on the left) Each segment has its own air and blood supply
40
Describe the pleurae
Smooth double layered membrane that covers each lung and lines the thoracic cavity Two pleurae are continuous at the root of the lung (hilum) Separated by thin film of fluid that allows pleurae to slide past each other without friction Fluid also prevents complete separation of the pleurae
41
Describe movement of the ribs during ventilation
Ribcage movement responsible for 25% air movement into and out of the lungs Active inspiration requires contraction of external intercostal muscles which run obliquely between ribs Passive expiration doesn't require muscular action. The ribcage relaxes back to its resting position During exercise, both sets of intercostal muscles become active and both inspiration and expiration require muscular action
42
Describe how the ribs increase the volume of the thorax
Ribs pivot around their joints with the vertebral column. Contraction of the external intercostal muscles lifts the ribs and rotates them around their pivot points. The ribs lift and swing upwards and outwards, increasing the volume of the thorax and allowing air in. The internal intercostal muscles run at right angles to the external intercostal muscles and when they contract they drag the ribs downwards - only for forceful exhalation.
43
Describe movement of the diaphragm during ventilation
Diaphragmatic muscle contracts which flattens the diaphragm and pulls the central dome down, increasing the volume of the thorax and causing inspiration. Passive relaxation of the muscle lifts the diaphragm back up towards the thorax reducing the volume and causing expiration. Responsible for 75% of bulk flow of air during quiet breathing.
44
Describe the diaphragm
The diaphragm is a dome shaped platform that forms the floor of the thorax and the roof of the abdomen. Its central part is a thin sheet of connective tissue (aponeurosis) called the central tendon. The lateral margins are fast acting skeletal muscle innervated by the phrenic nerve.