Respiratory Acidosis Flashcards
What is acidosis?
A situation in which the hydrogen ion concentration of arterial plasma is increased above normal (i.e. plasma pH is less than 7.35) whereas alkanosis denotes a decrease
What causes respiratory acidosis?
Failure to remove carbon dioxide from the blood
This can be due to inadequate ventilation or to the presence of significant amounts of carbon dioxide in inspired air
What kind of compensation can correct respiratory acidosis?
Renal compensatiom
Describe how renal compensation works
The decrease in pH causes an increase in hydrogen ion secretion into tue proximal convoluted tubule (via sodium- hydrogen antiporters) and collecting ducts (via hydrogen ATPases) and the increased reabsorption of bicarbonate ions which buffer the pH