Respiratory Flashcards
What is the histology of the respiratory tract in areas where the air needs to be filtered, warmed and moistened
PSUEDOSTRATIFIED CILIATED COLUMNAR EPITHELIUM
What is the histology of the respiratory tract in areas where food or debris may damage the respiratory tract?
STRATIFIED SQUAMOUS EPITHELIUM
What is the histology of the respiratory tract in areas where gas exchange can occur?
SIMPLE SQUAMOUS EPITHELIUM
Functions of the respiratory system?
- Provides a pathway for air into and out of the lungs
- Provides moist surface area (for gas exchange)
- Protects
- Produces sound
- Sense of smell
- Regulate PH
What are the components of the upper respiratory tract?
- Nose and nasal cavity
- Paranasal sinuses
- Pharynx
What are the components of the lower respiratory tract?
- Larynx
- Trachea
- Bronchi
- Bronchioles
- Lungs (alveoli)
What is the function of the nasal conchae?
To trap and humidify air and increase surface area
The nasal cavity is lined with two mucosa membranes, what are they?
Olfactory mucosa and Respiratory mucosa
What does Respiratory epithelium mean in context to its histology?
It refers to pseudostratified ciliated columnar epithelium. Sometimes with goblet cells in situations where we need mucous to protect or respiratory tract.
What epithelium type is in the respiratory mucosa of the nasal cavity?
Pseudostratified ciliated columnar epithelium with goblet cells.
Where does the olfactory mucosa sit?
On the superior regions of the nasal cavity
What does the olfactory mucosa contain?
Olfactory neurons and supporting epithelial cells
Function of nose and nasal cavities
Provides airway for respiration
Moistens and warms entering air using mucous lining
Filters and cleans air
Resonating chamber for air
What are the 4 paranasal sinuses?
Frontal, Sphenoid, Ethmoid, and maxillary
What are the functions of the paranasal sinuses in terms of the respiratory system?
Lightens the skull
Helps warm and moisten the air by producing mucous, which flows into the nasal cavity.
What is the order of the Pharynx from most superior to most inferior?
Nasopharynx
Oropharynx
Laryngopharynx
Which part of the pharynx is only meant to have air in it?
The nasopharynx
What epithelium does the nasopharynx have?
“respiratory epithelium”
pseudostratified ciliated epithelium
What part of the pharynx has openings for auditory tubes?
Nasopharynx
What epithelium does the oropharynx have?
Stratified squamous epithelium
because food is rough on epithelial cells until further digestion
What epithelium does the laryngopharynx have?
Stratified squamous epithelium
What structure does the laryngopharynx lead to?
Larynx
LARYNGO-pharynx
What is the larynx?
A cartilaginous tube that is attached to the hyoid bone.
What is the larynx also called?
The “voice box”
What are the structures of the larynx?
Thyroid cartilage Cricoid cartilage Epiglottis Vocal cords Glottis
What does the cricoid cartilage anchor the larynx to?
The trachea
What is the epiglottis’s nickname?
“guardian of the airway”
Where is the epiglottis located?
Ontop of the larynx
Function of the epiglottis?
Closes over larynx during swallowing to prevent food from entering airway
Function of vocal cords?
‘Folds’ over vocal ligaments that vibrate when air rushes up from the lungs
What is the glottis?
An opening between the vocal cords
Describe the key parts of the anatomy of the trachea
Strong hollow tube that is medial to the superior parts of the lungs.
Lined with ‘respiratory epithelium’ (pseudostratified ciliated columnar epithelium)
Has C shaped tracheal cartilaginous rings that are made of hyaline cartilage
What is special about the ‘C shaped’ tracheal cartilaginous rings of the trachea?
They have a posterior muscle called the trachealis muscle.
It consists of smooth muscle and it allows the trachea to constrict airway for a more forceful exhale.
What is a carina?
Is the last ‘c shaped’ tracheal cartilaginous ring.
It divides the trachea into left and right primary bronchi.
What is the pressure like while air is travelling through the bronchi?
The pressure increases as it goes from the primary bronchi to the 2ndary bronchi, and is at its most when it is in the tertiary bronchi.
What kind of epithelium do the bronchioles have?
Simple cuboidal epithelium.
What are the smallest branches of the bronchioles called?
Terminal bronchioles
What is an alveoli?
Thin-walled structures that are made for gas exchange.
It is surrounded by a network of capillaries and have elastin to allow for recoil in exhalation.
What are the 3 types of cells in the alveoli?
Type 1 pneumocytes
Type 2 pneumocytes
Alveolar macrophages
What is the histology of Type 1 Pneumocytes?
Simple squamous epithelium
What is the histology of Type 2 Pneumocytes?
Cuboidal epithelium
Function of Type 1 Pneumocytes?
Gas exchange
Function of Type 2 Pneumocytes?
Secrete a surfactant (lower surface tension)
What do alveolar sacs contain?
Alveoli
What is the function of Alveolar macrophages?
Protect epithelium
Where do the lungs sit?
In the left and right pleural cavities.
How do the lungs differ in size?
They differ in size because of the position of the heart.
The right lung has 3 lobes
The left lung has 2 lobes
What is “pulmonary ventilation”?
Breathing
What is the structure of the lungs that allow blood vessles, lymphatic vessels nerves and bronchi to enter called?
Hilum
Where is the Hilum located?
The most medial part of each lung. Where the bronchi stop.
What happens to the diaphragm during inhalation?
The diaphragm contracts (rises)
What happens to the diaphragm during exhalation?
The diaphragm relaxes (depresses)
Inhalation is _____
Exhalation is _____
Passive or Active
Inhalation is ACTIVE
Exhalation is PASSIVE
What are the 3 ways of getting air into the lungs?
Pulmonary ventilation
External respiration
Internal respiration
What happens during external respiration?
O2 moves from the air to the blood
CO2 moves from blood to air
What happens during internal respiration?
O2 moves from blood to tissues
CO2 moves from tissues to blood
Where does external respiration occur?
Capillary beds at alveoli
Where does internal respiration occur?
Capillary beds of the body
What are some impacts that occur in the respiratory tract that affect external respiration?
Pneumonia
Asthma
Emphysema
What is Asthma
Constriction of the bronchioles, reducing the volume of air that will enter the alveolar sacs
What causes asthma?
allergies or toxins
What is Emphysema?
Loss of alveoli in lungs
Reducing surface area for gas exchange
What causes Emphysema?
Smoking/Vaping or poor air quality.
What is Pneumonia caused by?
Viruses or bacteria
Why does Pneumonia happen?
Cytokins and fluids are brought to the lungs to protect them from viruses or bacteria.