Respiratory

Question 1

Which gene is associated with bronchiectasis?

Answer 1

HLA-DR1

Question 2

What is the normal function of the cystic fibrosis transmembrane regulator?

Answer 2

Chloride channel

Question 3

Which pathogen is most commonly associated with cavitating pneumonia?

Answer 3

Streptococcus pneumoniae

Question 4

What are the typical vital capacities for men and women?

Answer 4

4500ml in men

3500ml in women

Question 5

What is the common pattern of pneumonia seen in Klebsiella infection?

Answer 5

Cavitating pneumonia in upper lobes, often in alcoholics and diabetics

Question 6

What is a common complication of pneumocystis jiroveci pneumonia?

Answer 6

Pneumothorax

Question 7

Which causative agent of pneumonia is associated with reactivation of HAV?

Answer 7

Streptococcus pneumoniae

Question 8

What are the causes of upper lobe pulmonary fibrosis?

Answer 8

CHARTS:

• Coal-workers pneumoconiosis
• Histiocytosis/hypersensitivity pneumonitis
• Ankylosing spondylitis
• Radiation
• TB
• Silicosis/Sarcoidosis

Question 9

What is the role of alpha-1 anti-trypsin?

Answer 9

Protease inhibitor

Question 10

What average pulmonary arterial pressure is diagnostic of pulmonary arterial hypertension?

Answer 10

> 25mmHg

Or >30mmHg during exercise