Respiratory Flashcards
What is the difference between type 1 and type two pneumocytes?
type 1 thin- allows for gas exchange
type 2- much more round secretes surfactant
What is the main function of inter pleural fluid?
main function of inter pleural fluid is to generate surface tension ‘sticking’ the two together
What is more soluble oxygen or carbon dioxide?
carbon dioxide is known to be approximately 20-times more soluble than oxygen
What are the two states that blood can be transported around the body in?
blood can either be transported bound to haemoglobin or can be transported in plasma
What are the major species differences that are involved when comparing Hb O2 affinity?
small mammals have a low affinity- this promotes unloading at the site of the tissues
animals such as birds have a relatively higher affinity in comparison
What is the effect of temperature on oxygen affinity?
temperature reduce the affinity of Hb for oxygen
According to the pH Bohr theory what would the effect of decreasing blood pH be?
decreased affinity of haemoglobin for oxygen
What are the three main ways that CO2 is transported within the blood
Dissolved directly into the blood (the least)
Bound to Hb in erythrocyte as carbaminohaemoglobin (5-8%)
As HCO3- in blood (86-90%)
What is meant by the term the Haldane effect?
Binding of O2 to Hb decreases the affinity of Hb for CO2
What are peripheral chemoreceptors sensitive to?
CO2, O2 and pH
What are central chemoreceptors sensitive to?
CO2 (only)
