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YR3 Therapeutics > Respiratory > Flashcards

Respiratory Flashcards

1
Q

Examples of Beta 2 Agonists

A

Salbutamol

Salmeterol

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2
Q

Mechanism of Action of beta 2 agonists

A

Bind to and agonise Beta 2 Rceeptors in the airways, GI tract, uterus and blood vessels = dilation and relaxation.

Also increase activity of Na/K/ATPase pump so move K into intracellular environment

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3
Q

Indications for use of beta 2 agonists

A
  1. Asthma
  2. COPD
  3. Hyperkalemia (as an adjunct)
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4
Q

Side effects of bETA 2 AGONISTS

A

Signs of fight or flight:

Tremor
Anxiety
Tachycardia
Palps

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5
Q

Examples of antiuscuranics drugs

A

Titropium

Ipratopium

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6
Q

Mechanism of action of antimuscuranic drugs

A

Bind to the muscuranic receptor and so blocks the binding of ACh

Results in fight or fight responses at various sites:

  • dilation of pupils
  • reduce smooth muscle tone
  • reduce secretions from glands in resp/GI tract
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7
Q

Indications for use of antimuscuranic drugs

A
  1. COPD
  2. Asthma (adjunct with SABA)
  3. Dilating pupil
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8
Q

Contraindications for the use of antimuscuranic agents

A

Angle-Closure Glaucoma

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9
Q

Side effects of antimuscuranic agents

A

Dry mouth

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10
Q

Examples of mucolytics

A

Carbocysteine

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11
Q

Mechanism of action of mucolytics

A

Reduced goblet cell hyperplasia

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12
Q

Indications for use of a mucolytic

A

In conditions where these is a need to reduce the sputum viscosity

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13
Q

Contraindications of mucolytics

A

Peptic ulcer disease

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14
Q

Side effects of mucolytics

A

Stevens Johnson Syndrome

GI bleeding

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15
Q

Theophylines mechanism of action

A

Competitively inhibits type III and IV PDE which brings about bronchodilaton

Reduces airway responsiveness to histamine and allergens

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16
Q

Indications for use of theophyllines

A

COPD

Asthma

17
Q

Contraindications of theophylline

A

Caution in use in patients with cardiac disease

18
Q

Side effects of theophylline

A 
Nausea
tachycardia
headache
GI irritation
Diarrhoea
19
Q

Indications for the use of oxygen

A

Hypoxaemia
Pneumothorax
CO poisoning

20
Q

Mechanism of action of oxygen

A

Delivers more O2 to tissues
Forces N to be more readily released in pneumothorax
Competitively binds for haemoglobin

21
Q

Side effects of oxygen

A

dry mouth

22
Q

Contraindications for the use of oxygen

A

T2RF

23
Q

Which of the following is long acting and short acting

Tiatropium
Ipratropium

A

Tiatropium: short acting

Ipratropium: long acting

YR3 Therapeutics (8 decks)

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