Respiratory Flashcards
RFs for transient early wheezing?
Maternal smoking
Prematurity
What are the causes of childhood wheeze?
- Transient early wheezing
- Atopic asthma (IgE mediated)
- Non-atopic asthma
- Recurrent aspiration of feeds
- Inhaled foreign body
- CF
- Recurrent anaphylaxis in child with food allergies
- Congenital abnormality of lung, airway or heart
- Idiopathic
Features associated with asthma? Ie not early wheeze
- Sx worse at night and early morning
- Cough after exercise or early morning, disturbing sleep
- Sx that have a trigger i.e. pets, exercise, dust, cold air, emotions
- Interval symptoms ie sx b/w acute exacerbations
- Personal/family history of atopic disease
- Positive response to asthma therapy
Ddx of asthma
- Asthma
- GORD
- CF
- Viral induced wheezing (= early transient wheeze)
- Bronchiolitis
- Croup
Clinical features of moderate asthma?
- Marked pulsus paradoxus
- O2>92%
- PEFR >50% predicted or best value
- No clinical features of severe
Clinical features of severe asthma?
- Breathlessness interferes with talking
- O2 sats <92%
- Use of accessory neck muscles
- RR> 50/min age 2-5
- RR>30/min age >5
- HR>130/min age 2-5
- HR> 120/min age >5
- PEFR <50% predicted or best value
Clinical features of life-threatening asthma?
- Cyanosis, fatigue and drowsiness are all late signs
- Silent chest = emergency – child is about to arrest
- Poor respiratory effort
- Altered consciousness
- O2<92%
- PEFR<33% predicted/ best value
Management of acute asthma?
Moderate
– Short acting B2 agonist via spacer, 2-4 puffs, increasing by 2 puffs every 2 minutes to 10 puffs if required
– Consider oral prednisolone
– Reassess within 1h
Severe:
- Oxygen
- Give short acting B2 agonist 10 puffs via spacer or nebulizer
- Oral prednisolone or IV hydrocortisone should be given
- Nebulised ipratropium bromide if poor response
- Repeat bronchodilators every 20-30mins as needed
Life threatening:
– Oxygen
– Nebulised B2 agonist plus ipratropium bromide
– IV hydrocortisone
– The case discussed with a senior clinician and the PICU team
– Repeat bronchodilators every 20-30 minutes
Management of asthma in <5y?
Step 1 – Inhaled short acting B2 agonist as required
Step 2 – Add inhaled steroid 200-400mcg/day or leukotriene receptor antagonist if steroid cannot be used
Step 3 – Consider adding leukotriene receptor antagonist to inhaled steroid or visa versa
- In children under 2 consider moving to step 4
Step 4 – Refer to respiratory paediatrician
Management of asthma 5-12y?
Step 1 – Inhaled short acting B2 agonist as required
Step 2 – Add inhaled steroid 200-400mcg/day
- Start at dose appropriate to severity of disease
Step 3 – Add LABA and assess control
- If good then maintain
- Benefit from LABA but control still inadequate: continue and increase steroid to 400mcg/day
- No response: stop LABA and increase steroid to 400mcg/day, if this is still inadequate then trial leukotriene receptor antagonist or theophylline
Step 4 – Increased inhaled steroid to 800mcg/day
Step 5 – Use daily steroid tablet in lowest dose to give control whilst
maintaining inhaled steroid at 800mcg/day
- Also refer to respiratory paediatrician
What pathogen is most common in bronchiolitis?
RSV
Clinical features of bronchiolitis? S+S
- Coryzal sx precede dry cough and increasing breathlessness
- Feeding difficulty associated with dyspnoea often reason for admission
- Recurrent apnoea is a serious complication, esp in young infants
- Those born prem, with CLD, CF or congenital heart disease are most at risk of severe bronchiolitis
Characteristic clinical findings O/E include:
- Sharp dry cough
- Tachypnoea
- Subcostal and intercostal recessions
- Hyper-inflated chest (prominent sternum and liver displaced downwards)
- Fine end-inspiratory crackles
- High-pitched wheezes (expiratory>Inspiratory)
- Tachycardia
- Cyanosis or pallor
- Prolonged expiration
Management of bronchiolitis?
Humidified O2 through nasal cannula
Conc determined by sats
Fluids IV or NG if nec
Assisted ventilation (CPAP or nasal mask) if needed
Mist, abx, neb bronchodilators no benefit
Most recover within 2w
- 50% recurrence of cough/wheeze
- Occasional permanent lung damage
Common pathogens for pneumonia by age?
Newborns – organisms from mother’s genital tract:
- Group B strep
- Gram negative enterococci
Infants and young children:
- RSV = most common
- Strep pneumonia
- H.influenzae
- Bordetella pertussis and chlamydia trachomatis can also be a cause
- Infrequently staph aureus can be a cause and is very serious
Children over 5:
- Mycoplasma pneumonia
- Strep pneumonia
- Chlamydia pneumoniae
Suspect TB at all ages also
S+S pneumonia?
- Fever and difficulty breathing
- Usually preceded by URTI
- Cough, lethargy, poor feeding and an ‘unwell child’
- Chest, abdo/ neck pain –> pleural irritation- suggests bacterial
Signs:
- Tachypnoea, nasal flaring and chest indrawing
- End-inspiratory coarse crackles over affected area
- Classic signs of consolidation often absent in young children
- Decreased sats = indication for hospital admission