Respiratory Flashcards
Temperature of Nose
Same as inspired air
Functions of the Nose
Filter and Defense function
What are Turbinates
Small structures in the nose that cleanse and humidify air that passes through
What are the meatus’
Three spaces located underneath the three turbinates
Pneumatised areas of the paranasal sinuses
Frontal, Maxillary, Ethmoid and Sphenoid bones
What are the paranasal sinuses arranged into
Pairs
Where is the frontal sinus
Within frontal bone, over orbit and across superciliary arch
Nerve supply of Frontal sinuses
Opthalmic division of 5 nerve
Where are the Maxillary sinuses and what shape are they
Body of the Maxilla and pyramidal shape
Where do the Maxillary sinuses open into
Middle meatus and then the Hiatus Semilunaris
What is the Hiatus Semilunaris
Crescent shaped groove in the lateral wall of the nasal cavity
Where are the Ethmoid Sinuses
Between the eyes
What are the Ethmoid sinuses
A labyrinth of air cells
Nerve supply of Ethmoid sinuses
Opthalmic and Maxillary v Nerve
Where are the sphenoid sinuses situated
Medial to Cavernous sinus and interior to optic canal, dura and pituitary gland
Where do the Sphenoid sinuses empty into
Sphenoethmoidal recess
CF Class 1-3 explanation
1- no functional CFTR protein made
2-CFTR protein made but mis-folded (F508del)
3-CFTR protein formed into a channel but doesn’t open
CF genotype classifications class 4-6:
4-CFTR protein formed into a channel but chloride ions do not pass through
5-CFTR not made in sufficient quantities
6-CFTR protein with decreased cell surface stability
What is an Ivacaftor in treatment of CF, what does it do and what mutation is it effective for?
CFTR potentiator
Increases chloride secretion
Class 3 mutation
