Respiratory Flashcards
differentials of coughing dog
- Inflammatory diseases of the bronchi and the lungs (infectious or non-infectious)
- Tracheal/bronchial collapse
- Pulmonary edema (cardiogenic/noncardiogenic)
- Lung tumours
- Foreign body
- Haemorrhage
- Bronchial compression
chronic bronchtiis
Defined clinically as cough that occurs on most days of 2 or more consecutive months in the past year in the absence of other active disease
predisposition of chronic bronchitis
middle aged- older small breed dogs, cocker spaniels, terriers, poodles
cause of chronic bronchitis
unknown non specific/aspecific chronic bronchitis. Long standing inflammatory process initiated by infection, allergy or inhaled irritants or toxins
pathogenesis of chronic bronchitis
irritating factors chronic airway inflammation increased mucus secretion airway thickening bronchiectasis
signs of chronic bronchitis
loud, harsh cough, mucus hypersecretion, exercise intolerance
diagnosis of chronic bronchitis
need to exclude: tracheal collapse, idiopathic pulmonary fibrosis, eosinophilic broncho pneumopathy, parasitic pneumonias, bronchial/pulmonary tumours, heart disease
- BALF cytology: lot of mucous, normal or hyperplastic bronchial epithelial cells, predomination of nondegenerated neutrophils, presence of bronchial cylinders, increased number of macrophages, goblet cells and lymphocytes
- bronchoscopy, radiohtaphy, cytology
treatment of chronic bronchtiis
maintained symptomatically
Glucocortioids
- decrease the mucosa inflammation and secretion of mucous
- act rapidly
- systemic and local usage
Methyxanthines
- theophylline and aminophylline can be used in combination with glucocorticoids
for cough suppression (antitussive drugs)
- butorphanol, hydrocone, codeine, phocodin
prognosis of chronic bronchitis
good if compliant owner
complications of chronic bronchitis
bacterial or mycoplasma infection, tracheobronchomalacia, pulmonary hypertension and bronchiectasis
differentials of chronic bronchitis
bronchiectasis, CHF, airway foreign body, bacterial pneumonia, pulmonary edema, tracheal collapse
predisposition of feline asthma
Siamese + Burmese cats, more common in female and in young-middle aged cats
cause of feline asthma
allergens, exercise, physical/chemical factors, infection, drugs, stress
signs of feline asthma
cough, respiratory distress, long (forced) expiration, barrel shaped thorax, asymptomatic periods, lethargy, mucus swallowed after cough, increased airway sounds
diagnosis of feline asthma
- CBC – eosinophilia in 20% of cats, elevated stress leucogram
- biochemistry – Hyperglobinemia
- bronchoscopy: excessive mucus, roughened mucosa
- bronchial pattern, hyperinflation, straightening of the diaphragm, middle right lobe atelectasis
- microbiology of BALF
treatment of feline asthma
Emergency
- minimise stress, oxygen, rapid acting glucocorticoids (dexamethasone, methylprednisolone) bronchodilators (terbutaline/aminophylline), last resort: adrenaline
Glucocorticoids
- to control the inflammation in the airways and to stop/slow down the progression of the disease, inflammation is present in asymptomatic patients also
Bronchodilators
- methylxanthines: aminophylline/theophylline, they also have anti-inflammatory effects and increase mucocilliary clearance
- beta-2 agonists: salbutamol (fast acting), salmeterol (slow)
prognosis of feline asthma
dependent on response to treatment, if no response – euthanasia
differential of feline asthma
pulmonary edema, pneumothorax, lymphoma, anaemia, HCM, thromboembolism
predisposition of bacterial pneumonia
young animals < 1 years of age (spontaneous)
cause of bacterial pnuemonia
Bordetella bronchiseptica, strep, staph, E.coli, Pasteurella, klebsiella
signs of bacterial pnuemonia
cough (less common in cats), bilateral mucopurulent nasal discharge, exercise intolerance and respiratory distress, lethargy, anorexia, fever and weight loss
diagnosis of bacterial pneumoni
CBC, thoracic radiographic findings, tracheal wash fluid cytologic analysis and bacterial culture
- CBC = neutrophilic leucocytosis with a left shift, neutropenia with degenerative left shift
treatment of bacterial pneumonia
ATB and supportive care, airway hydration, physiotherapy, bronchodilators, expectorant (questionable), acetylcysteine
prognosis of bacterial pneumonia
more guarded in animals with underlying problems
complication of bacterial pneumonia
pulmonary abscess formation is an uncommon complication
cause of viral pneumonia
Distemper, canine influenzas, feline calicivirus, feline herpes virus
signs of viral pneumonia
lethargy, anorexia, tachypnoea, coughing, resp distress, collapse, exercise intolerance, increased lung sounds, crackles on lung auscultation, nasal and ocular discharge, fever
diagnosis of viral pneumonia
x-ray
- direct airway sampling transtracheal wash, bronchoscopy with BAL or fine needle aspiration of lungs
treatment of viral pneumonia
fluid therapy, supplemental oxygen, nutritional support, airway therapy (saline nebulisation for 5-10minx 3-4x daily followed by coupage)
Antimicrobial therapy
- puppy (outpatient) = doxycycline, puppy (inpatient) = ampicillin and gentamicin
- adult (OP) = co-amoxiclav/ fluoroquinolone and beta lactam combination, adult (IP) = ampicillin and gentamicin
- adult dog hospital acquired = carbapenems or 3rd gen cephalosporins
follow up of pnuemonia
repeat x-ray, stay in hosp until no longer oxygen dependent, treatment at home continue for 2-6 weeks and at least 1 week after complete resolution of clinical signs
prognosis of viral pneumonia
survival in puppy is 90%, older depends on underlying disease
cause of pleural effusion
can be blood (trauma, poison), chyle (thoracic duct rupture), exudate (bacteria into pleural space, bite etc), transudate (imbalance of absorption + filtration of fluid across pleura = hypoproteinemia) or modified transudate (long standing transudate, CHF)
pathogenesis of pleural effusion
luid accumulates, lung lobes retract and lung lobe borders become rounding
signs of pleural effusion
- problem in lower airways: pronounced + prolonged expirium, loud auscultation, whistles
- problem in upper airways: stridor +/or stertor, gasping, increased RR + labour, voice change, panting
- problem in lung parenchymal cyanosis, increased RR + labour, crackles, productive cough
- problem in pleural space: shallow breathing, Paradoxal breathing, muffled respiratory sounds
diagnosis of pleural effusion
radiography: fluid silhouettes the heart and diaphragm, obscuring their borders, displaced trachea dorsally
- thoracocentesis = detect fluid type (lower 1/3 = fluid, upper third = air)
- CBC – neutrophil with left shift in pyothorax
- cytopathology = for fluid type
o degenerate neutrophils and bacteria = pyothorax
o lymphocytes = chylothorax
o neoplastic cells = tumour