Respiratory 1 Flashcards

1
Q

Primary functions of resp system

A
  • exchange of gases between atmos and blood
  • regulation of body pH
  • protection of pathogens
  • vocalization
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2
Q

bulk flow

A
  • air flows from higher pressure to lower pressure
  • resistance is influence mostly by diameter of tubes
  • muscular pump creates pressure gradients
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3
Q

capacities

A

sum of 2 or more volumes

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4
Q

tidal volume

A

the amount of air in and out of the lungs at rest

~500mL

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5
Q

inspiratory reserve volume

A

additional air you can take in after resting inspiration

~3000mL

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6
Q

expiratory reserve volume

A

additional air you can exhale after quiet expiration

~1100mL

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7
Q

residual volume

A

amount of air left in lungs after maximal expiration

~1200mL

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8
Q

vital capacity

A
  • sum of IRV, TV, and ERV

- max amount of air that can voluntarily be moved in or out in one breath

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9
Q

total lung capacity

A

sum of all 4 volumes

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10
Q

functional residual capacity

A

ERV + RV

- capacity of air remiaining after quiet expiration

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11
Q

inspiratory capacity

A
  • the sum of IRV and TV

- the maximal amount of air that one can inspire

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12
Q

inspiration

A

occurs when alveolar pressure decreases

- increase in volume will cause a decrease in pressure

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13
Q

lung compliance

A

ability of the lung to stretch

- change in volume over change in pressure

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14
Q

elasticity

A

ability to resist being deformed

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15
Q

partial pressure

A

pressure contributed by a single gas in a mixture

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16
Q

why is intraplueral pressure negative

A

it is subatmospheric and the elastic recoil of the lungs and the outward pull of thoracic cavity. want to make the volume larger which decreases pressure

17
Q

when does inspiration occur

A

when alveolar pressure decreases

18
Q

when does expiration occur

A

when alveolar pressure increases

19
Q

muscles used for inspiration

A

external intercostals and scalenes

- diaphgram is mostly used

20
Q

muscles for forced inspiration

A

sternocleidomastoid
neck & back
upper resp

21
Q

muscles for forced expiration

A

abdominal
neck & back
internal intercostals

22
Q

lung compliance

A
  • ability of the lung to stretch

change in lung volume / chagne in pressure

23
Q

lung elastance

A

ability to resist being deformed

24
Q

high compliance

A

easily stretched but won’t return back to original shape

- need less change in pressure to expand lung

25
Q

low compliance

A

lungs are stiff and its hard to breathe in

- need extra inhalation

26
Q

decreased compliance disease

A

pulmonary fibrosis - caused by inhalation of pollutants

27
Q

increased compliance disease

A

emphysema

- loss of lung recoil, enzymes attack alveolar tissue

28
Q

surface tension

A

tension created by water molecules at air/water interface

29
Q

surfactant

A

secreted by type II alveolar cells

- decrease surface tension and increases compliance

30
Q

smaller alveoli needs more pressure to keep open as well as ___

A

more surfactant

31
Q

poiseuille’s law

A

r=8nl/(pi)(r^4)

32
Q

parasympathetic nerves innervate bronchiole smooth muscle by

A
  • Acetylcholine on muscarinic receptors (constriction)

- circulating epinephrine binding B2 adrenergic receptors (dilation)

33
Q

alveolar ventilation

A

ventilation rate x (tidal volume-dead space)

34
Q

total pulmonary ventilation

A

ventilation rate x tidal volume

- the effectiveness of ventilation