respiration

Question 1

drugs used in cough

Answer 1

anti tussives : codeine, pholcodine, noscapine, dextromethorphan, phenoxdiazine, anti histamines.
pharyngeal demulcents: lozenges
expectorants: sodium and potassium citrate.
mucolytics : bromhexine.

Question 2

drugs used in treatment of bronchial ashtma

Answer 2

1)bronchodilators :i) sympathomimetics : selective beta 2 agonists: salbutomol, terbutaline, bambuterol, salmeterol, formoterol.
non selective : adrenaline.
ii)methylxanthines : theophylline, aminophylline, etophylline, doxophylline.
iii)anti cholinergics : ipratropium bromide, tiotropium bromide.
2) leukotriene receptor antagonists : zafirlukast, montelukast, zileuton.
3) mast cell stabilizers : sodium cromoglycate, ketotifen
4) glucocorticoids : inhaled > beclomethasone
budesonide, fluticasone
5) anti Ige monoclonal Ab : omalizumab

Question 3

selective beta 2 agonist

Answer 3

salbutamol, terbutaline, salmeterol, formoterol.

Question 4

methylxanthines

Answer 4

theophylline and aminophylline. inhibit PDE and cause increase in CAMP then cause broncodilatation.

Question 5

leukotriene antagonist

Answer 5

montelukast , zafirlukast > inhibit cysteinyl-LT1 receptors.