Respiration Flashcards
What are the four stages of respiration?
Glycolysis, Link Reaction, Krebs Cycle, Oxidative Phosphorylation
What is the aerobic path of respiration?
Glycolysis, Link Reaction, Krebs Cycle, Oxidative phosphorylation
What is the anaerobic pathway of respiration?
Glycolysis , Fermentation
Give an overview of glycolysis
Glycolysis = sugar splitting
Glycolysis (6C) is split into two pyruvate(3C) molecules.
Glycolysis
- Explain phosphorylation
1)ATP is hydrolyzed to release a phosphoryl group so it can be added to glucose in order to activate glucose for the enzyme-controlled reaction.
Glucose -> Hexose monophosphate -> Hexose Biphosphate
Glycolysis
-Explain the Lysis stage
2)Hexose biphosphate -> 2x Triose phosphate
via hydrolysis
Glycolysis
-Explain the Oxidation stage
3)Dehydrogenase + coenzyme NAD hydrogen is removed from both triose phosphate molecules. H is accepted by both NAD molecules which causes them to be reduced (=NADH). Enzyme-controlled reactions convert both triose phosphate into pyruvate(3C) and in the process, 4ATP molecules are produced.
What are the stages of Glycolysis?
Phosphorylation, Lysis, Oxidation
What are the products of glycolysis?
2ATP (4 are produced but 2 are used in the initial phosphorylation of glucose)
2NADH
2Pyruvate
Where does glycolysis occur?
Cytoplasm of cells
Where does the link reaction and krebs cycle occur?
In the mitochondria
What is the overall purpose of the link reaction?
The oxidation of pyruvate.
What happens during the link reaction?
- Pyruvate in the cytoplasm is actively transported to the matric of the mitochondria.
- Pyruvate(3C) loses a CO2 molecule and two hydrogens and they are accepted by NAD to form NADH. This oxidizes the pyruvate to form acetate(2C).
- Acetate combines with coenzyme A to form acetylecoenzyme A.
Where does the Krebs Cycle take place?
The matrix of the mitochondria
What happens during the Krebs Cycle?
1)AcetylCoA(2C) combines with oxaloacetate(4C) to form citrate(6C).
2)Citrate is decarboxylated and dehydrogenated to form a 5C compound.
CO2 and NADH are released.
3)5c compound is decarboxylated and dehydrogenated again.
CO2 and NADH were released.
This causes substrate-level phosphorylation where one ATP is produced.
4)4C compound is dehydrogenated to produce reduced FADH2.
5)4C compound combines with a new Acetyl-coA.