resp quiz Flashcards by Shifa Usman

The following is a good choice for relieving headache in an asthmatic patient with aspirin hypersensitivity:
Aspirin Diclofenac Paracetamol ibuprofen prednisolone

paracetamol

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Which side effect of inhaled corticosteroids is reduced by spacer devices?
Cataracts Oropharyngeal candidiasis Thinning of skin Decreased bone density

Oropharyngeal candidiasis

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the following is useful for prevention of exacerbations in a patient with severe chronic bronchitis:
• Methylprednisolone • Prednisolone
• Cromolyn
• salbutamol
• roflumilast

• roflumilast

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The following class of drugs is indicated in severe COPD With frequent exacerbations is:
O Long-acting inhaled beta-2 agonists O Anticholinergics
O Inhaled corticosteroids
O Methylxanthines
O Short-acting inhaled beta-2 agonists

Inhaled corticosteroids

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Which medication is best to recommended for a 10-year-old patient with asthma, in addition to salbutamol MDI 1 or 2puffs every 4-6 hours as needed?
• Oral
• No additional therapy needed.
• Budesonide/formoterol MDI 80/4.5 mcg per puff 2 puffs
twice daily.
• Mometasone DPI

Mometasone DPI

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Which drugs are preferred for long-term treatment of moderate persistent asthma?
______________________
Which of the following drugs combinations is preferred for long-term management of moderate persistent asthma?:
• Zafiukast + Ipratropium
• Budesonide + Ipratropium
• Budesonide + salmeterol
• Aminophylline + formoterol

Budesonide + Formoterol

c) Budesonide + salmeterol

ICS + LABA

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How many seconds is optimal for breath holding after inhaling fromanMDI? 1 2 10 20 30

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10.A patient with COPD is expected to have:
O Increased TLC, decreased VC, increased FEVI /FVC ratio
O Increased TLC, decreased VC, decreased FEVI/FVC ratio
O Increased TLC, decreased VC, normal FEVI/FVC ratio
O Decreased TLC, increased VC, increased FEVI /FVC ratio

Increased TLC, decreased VC, decreased FEVI/FVC ratio

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The underlying pathophysiology of asthma is best described by which of the following statements?
• Asthma is a psychosomatic disorder.
• Asthma is a disorder of the lung parenchyma.
• Asthma is caused by an aberrant response to
vaccinations.
asthma is a disease of airway inflammation

asthma is a disease of airway inflammation

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Which objective measure for routine monitoring of asthma is available at home?
• PACO2 • FVC
• FEV1
• PEFR
• PD20

PEFR

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Oral medication are popular for the treatment of asthma in children because young children may have difficulty with the proper use of aerosol inhalers. Which of the following is an orally active drug used for asthma?
Ipratropium Cromolyn Salmeterol Montelukast

Montelukast

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Which of the following drugs does not have a direct bronchodilators effect?
Ipratropium Epinephrine Theophylline Prednisolone

Prednisolone

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Which of the following is best for management of acute exacerbations in patients with asthma or COPD who are nit responding adequately to inhaled bronchodilators?
Theophylline Prednisolone Roflumilast Fluticasone Cromolyn

Prednisolone

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Which objective measure for routine monitoring of asthma is available at home?

Which objective measure for routine monitoring of asthma is available at home? PEFR

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. All of the following are risk factors for COPD, EXCEPT:
• Passive cigarette smoke exposure
• Use of biomass fuels in poorly ventilated areas
• Coal dust exposure
• Recurrent respiratory tract infection

• Recurrent respiratory tract infection

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A 9-year-old child has severe asthma and was hospitalized 5 times between the ages of 7 and 9. He is now receiving outpatient medications that have greatly reduced the frequency of severe attacks. Which of the following is most likely to have adverse effects when used daily over long periods for severe asthma?

• Prednisolone by mouth

A 9-year-old boy has severe asthma and was hospitalized 6 times between the ages of6 and most likely to have adverse effects when used daily over long periods for severe asthma?
• Inhaled cromolyn
• Inhaled beclomethasone
• Inhaled montelukast
• Inhaled salbutamol

• Oral Prednisone

Which medications is best to recommended for 9-year-old girl with asthma, in addition to salbutamol MDI ?
• Oral theophylline
• No additional therapy is needed
• Mometasone DPI
• Budesonide/formoterol MDI

• Mometasone DPI

A 14-year-old girls symptoms were well controlled on SABA PRN+ mometasone. However, when winter arrived, she started using her salbutamol 3 or 4 days per week during the day. Which is the preferred treatment change?
• Add theophylline+ Montelukast orally.
• No change in therapy is needed.
• Switch to formoterol MDI
• Increase dose of mometasone DPI.

• Increase dose of mometasone DPI.

A 16-year-old male treated for bronchial asthma develops skeletal muscle tremors. Which of the following agents may be responsible for this finding?
Ipratropium zileuton salmeterol cromolyn Beclomethasone

salmeterol

A 20-year-old woman presents to the clinic with an asthma exacerbations. She states that she has been using her brothers salbutamol inhaler on a regular basis for the past2 years. During the past few months, she has been using the inhaler throughout the day on a daily basis and sometimes night. Which description best classifies her asthma severity.

Mild

persistent

.Which is the best asthma maintenance therapy for a 20-year- old patient using salbutamol inhaler throughout the day on a daily basis and sometimes at night?
• Zileuton.
• Fluticasone low dose.
• Fluticasone high dose.

• Fluticasone low dose.

A 23-year-old women is using salbutamol inhaler for frequent acute episodes of asthma and complains od symptoms that she ascribed to the salbutamol. Which of the following is not a recognized action of salbutamol?
Tachycardia Positive inotropic effect Diuretic effect Skeletal muscle tremor Smooth muscle relaxation

Diuretic effect

A 25-year-old woman is seen for follow-up of persistent asthma symptoms despite treatment with inhaled fluticasone 88microg twice daily for the past 3months, According to the Asthma treatment guidelines, which of the following changes in therapy can be considered?
• Addition of a leukotriene antagonist Addition of a low-dose theophylline Addition of a long-acting beta-agonist
• Increase the dose of ICS or add leukotriene antagonist or a LABA or low-dose theophylline.

Increase the dose of ICS or add leukotriene antagonist or a LABA or low-dose theophylline.

A 40-year-old women with moderate persistent asthma has been under good control for 3 months (currently using salbutamol MDI once weekly). She awakens at night twice monthly with asthma symptoms but continues to exercise regularly without difficulties. Her other medications include fluticasone inhaled 88microg/puff twice daily and salmeterol 50 microg twice daily. Her FEV1 is currently at 83% of her personal best. Which action is most appropriate at the present time? • Decrease the fluticasone to 44microg/puff twice daily • Discontinue the fluticasone • Do nothing, as the current salbutamol usage suggests poor asthma control • Discontinue the salmeterol • Add Montelukast 10mg once daily, as the current salbutamol usage suggests poor asthma control

Discontinue the salmeterol

• Discontinue the salmeterol

A 57-year-old woman with COPD was diagnosed with an upper respiratory tract infection. and erythromycin was prescribed. Her COPD was reasonably salbutamol. Which of the following would be an appropriate change in the patient s therapeutic regimen at this time? • • • • Add inhaled ipratropium to be used PRN. Add inhaled dexamethasone. Decrease the dose of theophylline. Add inhaled salmeterol.

Decrease the dose of theophylline.

Mr Green is a 60-year-old former smoker with cardiac disease and sever COPD associated with frequent episodes of bronchospasm. Which of the following is a bronchodilator useful in COPD and least likely to cause cardiac arrhythmia?

• Ipratropium

Mrs G attends the respiratory clinic for a review of her COPD, which seems to have worsened over the past 6 months. She is currently taking salbutamol PRN and stepping up of her treatment is considered. Which of the following is best option? Formoterol Beclomethasone Prednisolone Theophylline

Theophylline

A62-year-old man was recently diagnosed with COPD. Spirometry reveals EFV/1FVC60 % of predicated, pre-bronchodilators EFV 1 70% of predicated, and post-bronchodilator EFV1 72% of predicated. His symptoms are quite bothersome. He reports walking more slowly than others because of SoB and having to stop to catch his breath every so often when walking on level ground. He had 1 exacerbation last year that did not require hospitalization. Which is the most appropriate disease stage he is in according to guidelines? Stage1 stage2 Stage3 Stage4

stage2

.A 66 male patient with COPD (FEV1 39%) and a1-Antitryosin deficiency can benefit from:

• Weekly transfusions of a1-Antitrypsin augmentation | therapy

Mrs C is a 66-year-old former smoker with cardiac disease and severe COPD associated with frequent episodes of bronchoconstriction . which of the following is a bronchodilator useful in COPD and least likely to cause cardiac arrhythmia? Epinephrine zileuton salbutamol cromolyn tiotropium

tiotropium

A patient with asthma has moderate bronchospasm and wheezing about twice a week. Current medication are inhaler salbutamol used for prophylaxis and inhaled beclomethasone. If the physician chooses to use formoterol, which of the following is best way it should be used in the pateient management ? • A replacement for Beclomethasone • A replacement for salbutamol • The preferred agent for acute symptom control (rescue agent) • An add-on to current medications for additional prophylactic benefits • Primary (Sole) therapy, replacing both salbutamol and Beclomethasone

• An add-on to current medications for additional prophylactic benefits

A patient with chronic bronchitis is asking his local pharmacist for Dextromethorphan after an advice from a friend. Which information should the pharmacist teach the patient regarding this medications? • Dextromethorphan should not be used for a long period at it can cause addiction • Beta-2 agonist 2 should not be used while taking dextromethorphan • The patient should not drive or operate machinery while taking dextromethorphan • Dextromethorphan should not be used in case of chronic bronchitis as the coughing severs a good purpose by helping to clear sputum

Dextromethorphan should not be used in case of chronic bronchitis as the coughing severs a good purpose by helping to clear sputum