module 3 tablets crushing

Question 1

Name a light sensitive drug that is enteric coated to protect it from light

Answer 1

Nifedipine

Question 2

Changes in drug pharmacokinetics and bioavailabilty can be crucial for the following drug
Nifedipine 
Phenytoin(ans) 
Alendronate
Isotretenoin

Answer 2

Phenytoin

Question 3

How do extended release formulations work 3 points

Answer 3

Mixed release pellets that release the drug at different intervals
Multi layered drugs that release the drug as each layer is dissolved
Special matrixes that are inert but allow slow release of the drug

Question 4

Nitrofurantoin may cause \_\_\_\_\_\_\_\_\_\_\_\_\_ if it is crushed 
Teratogenacy 
Cancer 
Ulceration 
Constipation

Answer 4

Ulceration

Question 5

Name two examples of sugar coated drugs

Answer 5

Ibuprofen and quinine

Question 6

Name two examples of unpleasant tasting drugs that are film coated

Answer 6

Cefuroxme axetil

Ciprofloxacin

Question 7

______________ has an anesthetic effect on the tongue if given in powdered form.

Answer 7

Sertraline

Question 8

____________ and ____________ may result in NGT tube blockage if given after being crushed

Answer 8

Omeprazole and lansoprazole

Question 9

If a drug has to be crushed or manipulated to administer what is one precaution that must be followed and why?

Answer 9

Administer the drug as soon as possible to avoid the possibility of degradation and minimize risks.