RESP FAILURE Flashcards
TYPE 1 RESP FAILURE
- low level of oxygen
- normal level of carbon dioxide
CO2 build up
caused by a ventilation/perfusion (V/Q) mismatch; the volume of air flowing in and out of the lungs is not matched with the flow of blood to the lungs
CAUSES OF TYPE 1 RESP FAILURE CAN PROGRESS TO TYPE 2
cause of TYPE 1 RESP FAILURE
Low ambient oxygen (e.g. at high altitude)
Ventilation-perfusion mismatch (parts of the lung receive oxygen but not enough blood to absorb it, e.g. pulmonary embolism)
Alveolar hypoventilation (decreased minute volume due to reduced respiratory muscle activity, e.g. in acute neuromuscular disease); this form can also cause type 2 respiratory failure if severe
Diffusion problem (oxygen cannot enter the capillaries due to parenchymal disease, e.g. in pneumonia or ARDS)
Shunt (oxygenated blood mixes with non-oxygenated blood from the venous system, e.g. right to left shunt)
TYPE 2 RESP FAILURE
Failure of ventilation
- Decreased oxygen
- Increased carbon dioxide
Effect of vetilatory failure
- Low Ph, denatures enzymes from working
- worsening hypercapnia, lower arterial ph, development of acute resp acidosis
Causes of Type 2 resp failure
( chestwall and muscles)
- Guillian Barre syndrome - autoimmune disorder where it attacks peripheral nerves and causes paralysis
- Stroke - disturbance of brain tissue reduces drive to breathe