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CLASP > resp cancer > Flashcards

resp cancer Flashcards

1
Q

where is small cell lung cancer located

A

centrally, near the main bronchus

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2
Q

what is a risk factor for small cell lung cancer

A

smoking

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3
Q

what do small cell lung cancers secrete

A

ACTH and ADH

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4
Q

what does ACTH cause

A

cushings syndrom

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5
Q

what does ADH cause

A

increased water retention and increased BP

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6
Q

what lung cancer has the worst progosis

A

small cell

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7
Q

what are the non small cell lung cancers

A

squamous cellcarcinoma, adenocarcinoma, large cell, bronchial carcinoid

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8
Q

where are squamous cell lung cancers found

A

centrally located

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9
Q

what are risk factors for squmaous cells

A

smoking

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10
Q

what do squamous cell lung cancers secrete

A

PTH

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11
Q

what does PTH cause

A

hypercalaemia (brittle bones)

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12
Q

are sqaumous cells cavitating

A

yeeez

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13
Q

where are adenocarcinomas found

A

peripherally

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14
Q

who gets adenocarcinomas

A

non smokers

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15
Q

what do adenocarcinomas secrete

A

TTF

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16
Q

what gene is associated with adenocarcinomas

A

EGFR

17
Q

what tumour can form pancoast tumours

A

squamous and adenocarcinoma

18
Q

where are large cells found

A

throughout (peripherally)

19
Q

are large cells well or poorly differentiated

A

poorly

20
Q

what are some paraneoplastic features of lung cancer

A 
finger clubbin
hypertrophic pulmonary osteoarthropathy - HPOA
thrombophelbitis
hypercalaemia
SiADH
eaton-lambert syndrome
21
Q

what is HPOA

A

pain and tenderness of long bone due to elevation of peritoneum away from bone surface

22
Q

what is HPOA assocaited with

A

squamous cell

23
Q

what is thrombophelbitis

A

coagulability of blood in cancer patients eg painful saphenous vein

24
Q

what is hypercalcaemia

A

stones, ones, moans and phsychiatric overtones

25
Q

what is hypercalcaemaia related to

A

squamous cell

CLASP (3 decks)

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