Resp Flashcards
Classification of airflow limitation
- Mild: FEV1 >80% - but FEV/FVC 0.7 and syptomatic
- Mod: FEV1 50-79%
- Severe : 30-49%
- Very severe: Fev1
BODE index
Define: multidimensional tool to predict mortality in COPD
BMI
Obstruction: FEV1
Dyspnoea: MRC score
Exercise capacity - 6 minute walk
Light’s criteria
Used to diagnose of an exudative effusion
Effusion: serum protein ratio > 0.5
Effusion: serum LDH ratio > 0.6
Effusion LDH IS 0.6 time the limit of normal
Cause of pleural effusion.
Transudate - less than 25gL
- CCF
- renal failure
- low albumin: nephrotic syndrome, liver failure, enteropathy
- meig syndrome: right sided pleural effusion, ascites and ovarian fibroma
Exudate - protein > 35g/l
- infection: pneumonia, TB
- neoplasm: primary or secondary
- inflammation: RA, SLE
- infarction: PE
- trauma
Stages of clubbing
- Bogginess/increased fluctuate of nail bed
- Loss of concave nail fold angles
- Increased longitudinal and transverse curvature
- Soft tissue expansion of distal phalanx
Features of life threatening Asthma
CHEST Cyanosis Hypotension Exhaustion, confusion Silent chest, poor resp effort Tachyarrhythmia or bradyarrhytmias
PEFR4.6kpa, PaO2
Features of severe asthma
PEFR : 33-50%
Can’t complete sentences in one breath
RR>25
HR>110
Cause of pulmonary fibrosis
Environmental: asbestosis and silicosis
Drugs: bleomycin, amiodarone, nitrofuratonin, sulfasalazine, methotrexate
Hypersentivity: EAA
Infection: TB, viral,funghi
Associated systemic disease: sarcoid, RA, SLE, Systemic sclerosis, UC, anksponk, sjogrens
Kartageners syndrome
Situs inversus
Chronic sinusitis
Bronchiectasis
Young syndrome
Bronchiectasis
Rhinosinusitis
Azoospermia
mMRC Dyspnoea score
- SOB only on vigorous exercise
- SOB only on hurrying or walking up stairs
- Walks slowly or has to stop for breath
- Stops for breath after
CURB - 65
Confusion - AMTS less than on equal to 8
Urea - 7mM
Resp rate > 30/min
BP = 90/60
0-1 - home
2 - hospital
3 consider ITU
SIRS
Inflammatory response to a variety of insults manifest by >=2 of
- Temp >38 or 90
- RR> 20
- WCC >12x10^9 or less than 4
Sepsis
SIRS caused by localised infection
Severe sepsis
Sepsis with at least 1 organ dysfunction or hypoperfusion
Septic shock
Severe sepsis with refractory hypotension
MODS
Impairment of >=2 organ system
Homeostasis can not be maintained without therepeutic intervention
Complications of pneumonia
Septic Shock and multi organ failure
Para-pneumonic effusions/empyema
Abscess: S. Aureus, klebsiella, anerobes
Resp failure
Side effects of TB medication
Rifampacin: hepatitis, orange secretions, enzyme induction
Isoniazid: peripheral sensory neuropathy
Pyrazinamide: hepatitis, arthralgia
Ethambutol - optic neuritis - loss of colour vision first