Research In Medicine

Question 0

Animal model

Answer 0

Worms and flys -study genes
Worms - 40% genetic homology to human
Easy and cheap
Embryonic metabolism -turning on and off pathways
Flys - 65% to humans
Used in neuropharmacology to study effects of drugs and alcohol

Rats
Very social and intelligent
Often to study lifestyle on metabolism
Not a very good model for human infants

Mice
Popular for applying recombinant DNA technology (eliminate a gene)
Test importance of single protein
Lifestyle effects on metabolism
Mice take long to become insulin resistant on high fat diet

Question 1

Experimental model

Answer 1

Simulation with mathematic models/computer
In vitro and exvivo model (isolated cells and tissues )
Animal model
Humans

Question 2

Insulin -blood glucose will drop -glucose clears from blood

Lepton improves insulin levels

Answer 2

Qui

Question 3

Pigs used to study

Answer 3

Organ transplants

Best model for human infants development and metabolism

Question 4

Closest model to us is

Answer 4

Primates 
Could Learn 
Pathologies (AIDS) 
Transplantation 
Drug abuse toxicology

Question 5

Basic experiments on humans

Answer 5

Non clinical 
No treatment given 
Cannot prove cause and effect 
Only to predict association/correlation 
Epidemiological studies are most common 

Clinical traits
Evaluates effect of one or more health related interventions on health outcomes.

Question 6

Tests preformed to test a new drug safely.

Answer 6

Test on animals
Phase1 is it safe for humans
Phase2 is it effective for its purpose
Phase3 compare with other available treatments

Question 7

Evidence based medicine
The cochrane collaboration generates systematic review of primary literature most relevant but less available
Animal studies is where the info began

Answer 7

Righto

Question 8

Media accuracy

Animal protein is bad and causes cancer

Answer 8

Well study was done on rodents not humans

A lot that is not told

Question 9

Evolutionary medicine

Answer 9

Eat the way we used to eat? They died early
Little exercise inflammation in obesity
Flight of fight for survival ( faced with stress that we can’t do anything about)

Question 10

Integrative medicine

Answer 10

Healing oriented medicine
Includes all aspects
Emphasizes therapeutic relationship between practitioner and patient makes use of important therapies

Question 11

Collective medicine

Answer 11

One health mission statement recognizes human and animal health and mental health are inextricable linked
One healthy seeks improvement well being ect 7 dimensions

Question 12

Enhancement medicine

Answer 12

Has nothing to do with health Botox ect