research ebm Flashcards
COMPONENTS OF THE EBM CYCLE
A. Asking the Question B. Searching the Literature C. Appraising the Evidence D. Integrating the Data E. Making a Decision
PICOM components
Population to be studied
Intervention or exposure = Independent variable
Comparisons to be made (control)
Outcome of interest = Dependent variable Methodologic (study design)
Research question
PICOM
PIO
“To evaluate, to judge the value/worth”
APPRAISING THE EVIDENCE
COMPONENTS OF CRITICAL APPRAISAL
VALIDITY / LACK OF BIAS
SIZE & PRECISION OF EFFECT
APPLICABILITY & IMPACT
Will the results help me in caring for my patients?
APPLICABILITY & IMPACT
What are the results?
SIZE & PRECISION OF EFFECT
Is the study valid?
VALIDITY / LACK OF BIAS
W/ SYSTEMATIC ERROR
= BIASED
NOT VALID
Accuracy
Validity
Reliability
Precision
INTEGRATIVE STUDY DESIGNS
REVIEWS
OVERVIEWS
META-ANALYSIS
GUIDELINE DEVELOPMENT
results of trials are combined statistically
META-ANALYSIS
The PRIME requirement of any study
Validity
= W/ RANDOM ERROR
= LOW SAMPLE SIZE
Precision