Reproductive/GU Flashcards
Drug class for Folic Acid
water soluble vitamin
Indications for Folic Acid
supplement to prevent neural tube defects
MoA for Folic Acid
required for formation of multiple co-enzymes in protein synthesis
Drug class for Pyridoxine + Doxylamine
anti-nauseants
Doxylamine=antihistamine
Pyridoxin=Vit B6
Indications for Pyridoxine + Doxylamine
N/V in pregnancy
MoA for Pyridoxine + Doxylamine
inhibits CRTZ; diminishes vestibular stimulation; depresses labyrinthine function; sedating
Drug class for Methyldopa
anti-hypertensive: central alpha adrenergic inhibitor
Indications for Methyldopa
HTN in PG
MoA for Methyldopa
central alpha-adrenergic inhibition decreasing sympathetic outflow to heart, kidneys, peripheral vasculature
Drug class for Labetalol
anti-hypertensive: non-selective alpha1 & beta receptor blocker
Indications for Labetalol
HTN in PG
MoA for Labetalol
blocks alpha, beta1, beta2 adrenergic receptors
Drug class for Magnesium sulfate
tocolytic agent
Indications for Magnesium sulfate
premature labor/eclampsia; seizure; torsade de pointes; severe Mg deficiency; unresponsive status asthmaticus (kids)
MoA for Magnesium sulfate
decreased AcH in motor nerve terminals; slows rate SA node impulse formation; relaxation of bronchial smooth muscle
Drug class for Loestrin Fe 1/20
COC: monophasic
Drug class for Lo Loestrin Fe
COC: biphasic
Indications for Loestrin Fe 1/20 & Lo Loestrin Fe
contraception
Drug class for Triphasil
COC: triphasic
Drug class for Natazia
COC: quadriphasic
Indications for Triphasil & Natazia
contraception, peri-menopause
MoA for Loestrin Fe 1/20, Lo Loestrin Fe, Triphasil, Natazia
suppression of FSH, LH w/ suppression of ovulation, & reduced implantation, thickening cervical mucus, decrease tubal mortality
Drug class for Ovrette
Progestin-only OC
Indications for Ovrette
contraception; especially in women where COC is contra-indicated
MoA for Ovrette
prevent mid-cycle FSH/LH surge, inhibit ovulation, inhibit implantation, thicken cervical mucus, slow tubal transport
Drug class for Lybrel
extended cycle OC
Indications for Lybrel & Quartette
contraception; women w/ menstrual related sxs (HA, menorrhagia, anemia, endometriosis-pain)
MoA for Lybrel & Quartette
prevent mid-cycle FSH/LH surge, inhibit implantation, thicken cervical mucus, slow tubal transport
Drug class for Quartette
quadriphasic ascending dose: extended cycle OC
Drug class for Conjugated Equine Estrogen CEE [Premarin]
Estrogen
Indications for CEE [Premarin]
moderate to severe vasomotor sxs; vaginal mucosal atrophy, hypogonadism
MoA for CEE [Premarin]
estrogen supplement
Drug class for MPA [Provera]
progesterone
Indications for MPA [Provera]
contraception; esp in women who have contra-indications for EE
MoA for MPA [Provera]
prevent mid-cycle FSH/LH surge, inhibit ovulation, inhibit implantation, thicken cervical mucus, slow tubal transport
Drug class for Mifepristone
abortifactant
Indications for Mifepristone
early pregnancy termination
MoA for Mifepristone
inhibits progesterone receptors, antagonizing endometrial & myometrial effects
Drug class for Ulipristal
post exposure contraception
Indications for Ulipristal
emergency contraception
MoA for Ulipristal
binds to progesterone receptor, inhibiting or delaying ovulation; alters endometrium possibly preventing implantation