reproductive/genitourinary pharm

Question 1

oral contraceptives

Answer 1

-combo estrogen & progesterone
-ethinyl estradiol and norethindrone
-ethinyl estradiol and norehthindrone

Question 2

oral contraceptives moa

Answer 2

-mimics natural hormones but remain constant, rather than fluctuate, FSH and LH suppressed, ovum unable to attach to the uterus
-prevents thickening of endometrium so even if ovulation occurs, the ovum cant attach to the uterus

Question 3

oral contraceptives ae

Answer 3

-risk for thromboembolism
-uterine bleeding
-promotes growth of existing breast cancer
-htn

Question 4

oral contraceptives interventions

Answer 4

-monitor for thrombosis
-encourage smoking cessation
-monitor k+ levels of those taking ethinyl estradiol and drospirenone for hyperkalemia
-monitor bp
-monitor pattern and amt of uterine bleeding
-recommend mammograms for those with risk of breast cancer
-educate not to take if pregnant, pregnancy test before admin

Question 5

oral contraceptives contraindications/precautions

Answer 5

contraindication
-during pregnancy
-at risk for thromboembolic events
-suspected/confirmed breast cancer
caution
-htn
-dm
-heart disease
-migraine headaches

Question 6

estradiol hormone replacement therapy drugs

Answer 6

-equine estrogen
-transdermal estradiol
-estradiol intravaginal tablets
-estradiol cream

Question 7

estradiol HRT moa

Answer 7

substitutes normal amounts of estrogen in the premenopausal female with smaller amounts to prevent menopausal sx

Question 8

estradiol HRT ae

Answer 8

-nausea, decrease with continued use
-htn
-endometrial hyperplasia
-increased risk for endometrial and ovarian cancers
-risk for thromboembolic disorders

Question 9

estradiol HRT interventions

Answer 9

-educate to take the same time each day to avoid monthly bleeding
-apply patches at recommended interval, 1-2x a week, on abdomen or trunk, press firmly for 10 seconds

Question 10

estradiol HRT contraindications/precautions

Answer 10

contraindicated
-risk for thromboembolic events
-suspected or confirmed breast, vaginal, cervical, or endometrial cancer
-liver disease
-undx vaginal bleeding
caution
-htn
-gallbladder dx
-dm
-heart disease
-migraine h/a
-kidney dysfunction

Question 11

estrogen and progesteron HRT drugs

Answer 11

-conjugated estrogen and medroxyprogesterone acetate
-transdermal estradiol
-norethindrone

Question 12

estrogen and progesteron HRT use

Answer 12

-relief of postmenopausal sx (vasomotor), and vulvar and vaginal atrophy
-prevention of postmenopausal osteoporosis

Question 13

estrogen and progesteron HRT ae

Answer 13

-thromboembolism
-nausea
-htn
-breast cancer
-breakthrough bleeding and other menstrual irregularities
-edema

Question 14

estrogen and progesteron HRT interventions

Answer 14

-monitor for DVT
-encourage to stop smoking
-monitor bp
-recommend mammograms
-d/c for any indications of breast cancer
-monitor edema and weight gain