[SUB] DRUGS ASSOCIATED WITH FEMALE REPRODUCTIVE CYCLE Flashcards
1
Q
- gnrh agonists
- continuous fashion
- lower FSH and LH = lower estrogen and testosterone
- for endometriosis, prostate cancer
A
gnrh analog
2
Q
- no start up flare
- for prostate cancer
A
gnrh antagonist
3
Q
- binds to estrogen receptors
- for hypogonadism, ovarian failure, messtrual abnormalities, hormone replacement therapy
- increased risk of endo. cancer and menopausal bleeding
A
estrogen
4
Q
- block estrogen from connecting with other receptors
- multitaskers
A
selective estrogen receptor modulators
5
Q
what are the 3 ER antagonists
A
clomiphene, tamoxifen, raloxifene
6
Q
- prevent conversion of androgens to estrogen
- for ER breast cancer
A
aromatase inhibitors
7
Q
- bind progesterone receptors
- less growth and more vascularization of endometrium
- thicken cervical mucus
- for contraception, endo. cancer, uterine bleeding
A
progestins
8
Q
- progestin inhibitor
- for termination, emergency contraception
A
antiprogestins
9
Q
- LH / FSH inhibitor
- no ovulation
- progestin thickens cervical mucus = limited sperm access
A
progestin and ethinyl estradiol (combined)
10
Q
- local inflammation toxic to sperm and ova
- prevent fertilization and implantation
- hormone free
- long acting contraception, emergency contra.
A
copper IUD
11
Q
- androgen receptor agonists
- treat hypogonadism and development of secondary sex charac.
A
testosterone, methyltestosterone
12
Q
- synthetic androgen
- for endometriosis and angioedema
A
danazol
13
Q
- er antagonist at hypothalamus
- higher LH, FSH
- for infertility
A
clomiphene
14
Q
- er antagonist at breasts
- partially at uterus and bone
- for er breast cancer
A
tamoxifen
15
Q
- er antagonist at uterus and breast
- agonist at bone
- for osteoporosis
A
raloxifene
