DRUGS ACTING ON THE IMMUNE SYSTEM Flashcards
- decreasing virus level to an undetectable levels
- preserving and increasing the number of CD4+ T cells
- preventing resistant
- having client in good clinical condition
- preventing secondary infections and cancers
HAART - highly active antiretroviral therapy
- reduce the detectable viral load of HIV RNA as low as possible
- maintain this level of suppression for as long as possible
- prevent opportunistic infections
antiretroviral therapy
- force the HIV virus to use faulty versions of building blocks so infected cells cant make more HIV
NRTIs - nucleoside/tide reverse transcriptase inhibitors
- also called “non-nukes”
- they bind to a specific protein so the HIV virus cant make copies of itself
NNRTIs - non-nucleoside reverse transcriptase inhibitors
- these drugs block a protein that infected cells need to put together new HIV virus particles
PIs - protease inhibitors
- these stop HIV from making copies of itself by blocking a key protein that allows the virus to put its DNA into healthy cell’s DNA
integrase inhibitors
- unlike NRTIs, NNRTIs, PIs, and INSTIs, which work on infected cells, these drugs block HIV from getting inside healthy cells
fusion inhibitors
- new class of drug with just on medication, fostemsavir
- for adults who have tried multiple HIV meds and whose HIV has been resistant to other therapies
- targets the glycoprotein 120 on the virus surface
- stops it from being able to attach itself to the CD4 T-cells
gp120 attachment inhibitor
- maraviroc or MVC
- stops HIV before it gets inside a healthy cell, but in a different way than FIs
- blocks a specific kind of hook on the outside of certain cells so the virus cant plug in
CCR5 antagonist
- new class of antiviral medication specifically for adults living with HIV who have tried multiple HIV medications and whose HIV has been resistant to other therapies
- ibalizumad-uiyk blocks your body’s HIV infected cells from spreading the virus into those which are uninfected
post-attachment inhibitor / monoclonal antibody
pharmacologic enhancers are also called ___
drug boosters
___, taken in a low dose, increases blood levels of lopinavir (LPV) and the drug LPV/r
ritonavir
some manufacturers put together specific medicines into a single pill so theyre easier to take
fixed-dose combinations
you takes these meds before HIV gets into your system to help protect against infection
PrEP - pre-exposure prophylaxis
HIV medicines taken very soon after a possible exposure to HIV to prevent the virus from taking hold in your body
PEP - post exposure prophylaxis
