Reproductive Flashcards
Defined by sex chromosomes
Genetic sex
Defined by presence of testes/ovaries
Gonadal sex
Defined by characteristics of internal genital tract and external genitalia
Phenotypic sex
Internal genital tract: males
Prostate, seminal vesicle, bas deferens, epididymis
Internal genital tract: females
FT, uterus, upper 1/3 vagina
External genitalia: males
Scrotum, penis
External genitalia: females
Clitoris, labia minora, majora & lower 2/3 vagina
Secreted by sertoli cells to cause atrophy of mullerian ducts
Antimullerian hormone
Secreted by leydig cells for growth of wolffian ducts
Testosterone
Which substance is suspected to initiate puberty?
Melatonin
What conditions may inhibit the onset of puberty?
Stress, Malnutrition
What is the first event in puberty?
Males: Testicular EnlargementFemales: Breast Enlargement
Which hormone causes adrenarche (pubic hair, axillary hair development) in females?
Adrenal androgens
For sperm production
Seminiferous tubules
For sperm maturation, motility
Epididymis
For sperm storage
Vas deferens
For sperm nutrition
Seminal vesicle
For semen alkalinity
Prostate gland
Supplies mucus
Urethral glands, Bulbourethral glands
Testes temperature
1-2 degree celsius cooler
Responsible for testes temperature
Countercurrent exchange testicular blood vessels
Duration of spermatogenesis
64 days
Sperm production per day
128 million
“Activation” of sperm in the female; Genital Tract for 4-6 hours
Capacitation
Enzyme that convert androstenedione to testosterone
17beta-hydroxysteroid dehydrogenase
Enzyme that convert testosterone to dihydrotestosterone
5alpha-reductase
5alpha-reductase inhibitor used for male pattern baldness and BPH
Finasteride
Cell which determines sex of the baby
Sperm cell
Part of the cell that contains hyaluronidase, proteolytic enzymes
Acrosome
Acrosome comes from which organelle
Golgi apparatus
Definition of low sperm count
<20 million sperm/ml
Sequelae of Cryptorchidism
Infertility, Testicular cancer
Loss of body hair, musculature, thick bones, decreased libido
Castration (after puberty)
Vestigial remnant of 3rd eye; secretes melatonin which is involve in reproduction and sex drive
Pineal gland
Ovum surrounded by single layer of granulosa cells
Primordial Follicle
Provides nourishment to ovum; Secretes inhibiting factor to keep ovum in Prophase
Granulosa Cells
Larger ovum, with more layers of granulosa cells; Develop the layer from ovarian interstitium
Primary Follicle
Secrete estrogen & progesterone
Theca interna
Becomes capsule of the follicle
Theca Externa
1-1.5cm in size
Mature follicle
Secreted by adrenal cortex and thecal cell
Estrone
Secreted by ovaries
Estradiol
Secreted by ovaries
Estriol
Enzyme that catalyzes conversion of Androstenodione to Esteone and Testosterone to Estradiol
Aromatase
Estrogen predominates
Follicular Phase
Progesterone predominates
Luteal Phase
Stromal and epithelial cells proliferate; thin, stringy, (+) ferning
Proliferative Phase
Increased tortuosity of glands and blood vessels; thick, non-elastic, (-) ferning
Secretory Phase
Due to cessation of Progesterone; (+) necrosis of endometrium, bleeding, desquamation
Menses
Produced by ovarian granulosa cell and inhibits FSH secretion from ant pituitary
Inhibin
Produced by ovarian granulosa cell and stimulates FSH secretion from ant pituitary
Activin
Average age menarche, menopause
13yo & 45yo
Number of lifetime mature follicles
400 follicles
Peak of sexual desire
Just before ovulation
Helps in fertility
Female orgasm
Fertilized ovum implanting on uterus
Blastocyst
Cells of the blastocyst that digests and liquefies the endometrium for invasion
Trophoblast
Produced by Syncitiotrophoblast
Beta-HCG
Produced by Fetal Adrenal Gland
Estrogen
Promote growth of fetus; Growth hormone of pregnancy
Human Chorionic Somatomammotropin (HCS) aka Human Placental Lactogen (HPL)