Reproduction Flashcards
Gonadotropin-releasing hormon (GnRH)
- Peptide number
- Role, Where produced
- GnRH-I vs GnRH-II
3
4
Where are GnRH neurons formed in early fetal development + where do they go
- How do they migrate
- Where do I, II, and III migrate to?
6
8
Kallman’s syndrome
12
GnRH neuron high frequency and amplitude pulse vs low frequency - Do they favour LH or FSH more?
- How do arcuate nucleus (ARC) and antero ventral periventricular nucleus (AVPV/PeN) regulate this?
- How kisspeptin gets enviro signals (3)
14
Kisspeptin (KP) neuron
16-17
19
Kisspeptin regulation of GnRH pulse development:
- Perinatal
- Juvenile
- Peripubertal
- Pubertal
18
Gonadotropin inhibiting releasing hormone (GnIH)
- Hamster vs quail
- Why is it important to inhibit GnRH during stress or winter
20
LH and FSH secreted by what in mammals, teleost fish, cartilaginous fish
- Known as what in fish
CG secreted by what in animals
22
Male reproductive endocrinology feedback:
- FSH -> Sertoli cells
- LH -> Leydig cells
25-26
Female reproductive endocrinology:
- Estradiol (E2) and progesterone (P) feedback
- Inhibin + Follistatin vs Activin feedback
27
Phases of ovarian cycle:
- Follicular phase
- Ovulation
- Luteal phase
29-30
Ovulatory cycle of sheep vs elephant
31
Follicular phase (early)
- FSH -> Granulosa cells
- LH -> Thecal cells
Late follicular and luteal phases
- High E2
- Progesterone
- Inhibin AB
32-33
Production of sex steroids w/ LH and FSH
(cholesterol-> androgen -> estrogen)
34
Production of sex steroids in testes vs ovary;
- Leydig cell -> Cholesterol -> Pregnenolone -> Testosterone (sertoli cell) -> Estradiol
- Thecal cell -> Cholesterol -> Androstenedione testosterone -> estradiol (granulosa cell)
39
