Repro VI Flashcards
leiomyoma
fibroid of endometrium
higher in AAs
B9 smooth m tumor
estrogen sensitive - increased with pregnancy, decreased with menopause
endometriosis
endometrial gland outside uterus
can be anywhere
ovary - chocolate cyst
cyclic pelvic pain, bleeding, dysmenorrhea, dyspareunia, infertility
tx of endometriosis
NSAID OCP progestin GnRH agonist danazol
laparoscopic removal
endometritis
inflammation of endometrium
with retained product of pregnancy or foreign body
tx - gentamicin or clincamycin
endometrial hyperplasia
too much estrogen stimulation
risk of endometrial carcinoma
endometrial cancer
MC gyn malignancy
55-65yo women
risk fx - unopposed estrogen, obesity, DM, HTN, nulliparous, late menopause, lynch syndrome
fibroadenoma
B9 breast tumor
of stroma
intraductal papilloma
B9 small tumor in lactiferous duct of breast
secrete bloody and serous nipple discharge
risk of carcinoma
phyllodes tumor
B9 large bulky breast mass - CT and cysts
leaf like projection
often 5th decade
may become malignant
proliferative breast disease
fibrosis - hyperplastic stroma
cystic - fluid filled - ductal dilation
sclerosing adenosis - more acini and fibrosis - calcify
epithelial hyperplasia - epi layers in term duct lobule
lactation mastitis
during breastfeeding
higher risk bacterial infection - cracks in nipple
staph aureus - MC pathogen
tx dicloxacillin
fat necrosis
B9 painless lump
-after trauma to breast
abnormal calcification
gynecomastia
breast large in males
hyperestrogen
klinefelters, drugs, physiologic
malignant breast tumors
postmenopause
overexpression - c-erbB2 (Her2)
triple negative - more aggressive
axillary nodes - mets - most important prognostic factor
most often upper outer quadrant of breast`
risk malignant breast ca
estrogen older age 1st birth obesity BRCA1 and 2 AA
ductal carcinoma in situ
fill ductal lumen
from ductal atypia
see early as microcalcifications
comedocarcinoma
ductal central necrosis
subtype DCIS
paget disease
underlying DCIS
or invasive breast ca
eczematous patch on nipple
paget cell - large cell in epidermis with halo
extramammary - on vulva
invasive ductal carcinoma of breast
worst and most invasive and MC
firm fibrous rock hard mass sharp marins
stellate infiltration
invasive lobular breast tumor
orderly row of cells - indian file
los E-cadherin
inflammatory breast cancer
dermal lymph invasion
get pea d’orange
-when block lymph drainage
50% survival 4 years
peyronie disease
fibrous plaque of penis
with ED
priapism
longer than 4 hours - painful
association - trauma, sickle cell, meds
tx with corporal aspiration
SCC of penis
asia, africa, s. america
bowen disease - precursor
association with HPV and lack of circumcision
