repro / hormones Flashcards
examples of GnRH agonists/antagonists
agonist - leuprorelin
antagonist - cetrorelix, elagolix
examples of 5-a-reductase inhibitors
finasteride, dutasterid
examples of aromatase inhibitors
anastrozole
formestane
examples of SERMs
tamoxifen
raloxifene
clomiphene
examples of androgen receptor antagonists
flutamide - hydroxyflutamide
spironolactone
example of full ER antagonist
fulvestrant
preterm labour drugs
CCBs - nifedipine
oxytocin analoge - atosiban
b2 - salbutamol
cox inhibitor - indomethacin
labour inducing
oxytocin
dinoprostone
postpartum haemorrhage
ergotamine malaete
oxytocin
medical abortion
misoprostal
mifepristone
erectile dysfunction
pde-5 inhibitors - silden, tada, vardenafil
pge1 analgoue - alprostadil
drugs to give if u got excess prolactin
dopamine agonists - D2 - e.g. carbegoine, bromcriptine as this can inhibit lactotroph growth in the pituitary gland
spit out the drugs you know that help regulate the growth hormone pathway
not enough GH (acquired or pituitary got problem)
somatropin - recombinant GHRH (for replacement therapy)
sermorelin - synthetic GHRH (for diagnostics)
mercasermin - recombinant IGF-1
for excess states (Acro Adult)
somatostatin - GHIH (stops TSH and GH)
octreotide / lanreotide - longer acting synthetic somatostatin analogues
pegvisomant - receombinant GH receptor antagonist
mineracorticoid agonists and antagonsits
aldosterone receptor antagonists - spirinolactone, eplerone
s also androgen antag - can lead to gynaecomastia
fludrocortisone (analogue of cortisol, but binds to MC with higher affinity than GC)
glucocorticoid analogue
hydrocortisone
prednisolone
dexamethasone
beclomethasone (lipoxin)
fluticasone
