REPRO

Question 0

Condyloma Latum

Answer 0

Secondary Syphilis

Question 1

Condyloma Acuminatum

Def’n?

Answer 1

Benign warty growth on genital skin + Koilocytes.

HPV 6 or 11

Question 2

CIN & Cervical Carcinoma In Situ

Def’n, Classification, Mech (2), RF (4), Prog / Comp?

Answer 2

HPV (DNA virus that infects lower genital tract,
esp cervix in transformation zone).
- High-Risk HPV types: 16, 18, 31, 33
- Low-Risk HPV types: 6, 11

Cervical dysplasia (disordered epithelial growth) that begins at
basal layer of squamo-columnar junction (transformation zone) and
extends outwards.

Classified as CIN I, II or III depending on extent of dysplasia.

MECH:

• HPV 16 -> produces E6 protein -> destruction of p53
• HPV 18 -> produces E7 protein -> destruction of Rb

RF:

• Immunodeficiency / HIV
• Early sexual intercourse
• Multiple sexual partners
• Smoking

PROG:

• Infection usually eradicated by acute infl *
• Persistent infection -> CIN -> Carcinoma

Question 3

Squamous Cell Carcinoma (SCC)

MC Locations (2)?

Answer 3

HPV.

• Cervix
• Anus (gay men)

Question 4

Acute Mastitis

Answer 4

S aureus

Question 5

Acute Prostatitis / Orchitis in Young Adults (3)

Answer 5

• Chlamydia trachomatis (serotypes D-K)
• Neisseria gonorrhoeae
• Mumps virus Orchitis only

Question 6

Acute Prostatitis / Orchitis in Older Adults (2)

Answer 6

• E coli

- Pseudomonas

Question 7

Lymphogranuloma Venereum

Def’n, Pres, RX?

Answer 7

NECROTIZING / ULCERATING granulomatous infl of the inguinal lymph nodes.
Eventually heals with FIBROSIS.

Chlamydia trachomatis (serotypes L1-L3).

PRES = Small painless ulcers on genitals ->
Swollen + ulcerating + PAINFUL inguinal lymph nodes.

RX = Doxycycline

Question 8

PID (2)

Answer 8

• Chlamydia trachomatis (subacute- often undiagnosed)

- Neisseria gonorrhoeae (acute)