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Pathology Test 1 > Repair > Flashcards

Repair Flashcards

1
Q

Describe the timeline for inflammation in the skin. Day one.

A

Clot and neutrophils.

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2
Q

Describe the timeline for inflammation in the skin. Day 2

A

Epithelial cells migrate under clot.

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3
Q

Describe the timeline for inflammation in the skin. Day 3

A

Macs replace neutrophils.

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4
Q

Describe the timeline for inflammation in the skin. Day 4

A

Fibroblast follow macs

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5
Q

Describe the timeline for inflammation in the skin. Day 5.

A

Angiogenesis.

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6
Q

Fibroblasts and angiogenesis are collectively called

A

Granulation tissue

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7
Q

Describe the timeline for inflammation in the skin. Day 7-14

A

Increased collagen and lower fibrin clot.

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8
Q

When is the collagen the highest?

A

1 month.

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9
Q

When’s the strength reach its peak?

A

4 months

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10
Q

What causes contracture?

A

Myofibroblasts.

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11
Q

Keloids are causes by

A

Increase fibroblast activity. There’s no remodeling.

Timp are over active and inactivate the regulator for collagen (mmt which is a zn cofactor)

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12
Q

Describe the timeline for inflammation in the heart.

A

1: monocytes.
2: macs
3: angiogenesis
4: fibroblasts
5: collagen.

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13
Q

What growth factor is only involved with fibroblasts?

A

EGF (endothelial)

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14
Q

When is the PDGF released?

A

When platelets hit the ECM.

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15
Q

What’s PDGF do?

A

Increases fibroblasts
Collagen
Monocytes

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16
Q

What does TGFb do?

A

Most important fibroblast gf.

Increase collagen and monocytes

17
Q

VEGF is involved with what?

A

Angiogenesis

Comes with granulation tissue

18
Q

FGF Is what?

A

Released by fibroblasts and increases fibroblasts, monocytes, and angio.

No Collagen.

19
Q

Which GF involve collagen?

A

PDGF

TGFb

20
Q

Mac 1 released what? Whats a Mac 1 do?

A

Il 1 and 2 and 23

Proinflamm

21
Q

What’s a Mac 2 do?

A

Repair.

Also releases TGFb

22
Q

Anastomoses is?

A

Tubuluar connection between two tubes

23
Q

Adhesion?

A

Abnormal connection of fibrin followed by collagen

24
Q

Fistula

A

Abnormal connection with a lumen

25
Q

Hernia

A

Abnormal Protrusion

26
Q

What is a Labile cell? Characteristics? Where are some?

A

Labile is always replicating. Mucosa and epithelium. Epiderm

27
Q

What’s a stable cell? Characteristics? And where?

A

Able to replicate if damaged but not continually. Mesoderm. Typically undergo hyperplasia. Liver.

28
Q

Permanent type cell? Example?

A

Brain and heart and not able to undergo regeneration.

Pathology Test 1 (7 decks)

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