Reovirus Flashcards
Genera of reovirus
Orthoreovirus
Rotavirus
Coltivirus
Orbivirus
Virus with large spikes
Spinareovirinae
Smooth and lacking the large surface projection
Sedoreovirinae
Major cause of infantile diarrhea
Rotavirus
Good models for melcular studies of viral pathogenesis
Reovirus
What is the antigenic epitopes on the internal structural protein
VP6
Reovirus can be detected by what
ELISA
IEM
PCR
What group is the most frequent pathogen
Group A
Epitopes that are neutralizing activity
VP4 and VP7
Serotypes that are responsible for the majority of human disease
G1-G4 and G9
What do reovirus infect
Small intestine
Viral enterotoxin and induces secretion by triggering a calcium dependent signal transduction pathway
NSP4
Seen among young children
Group A
Seen among adults
Group B
Protective against rotavirus infection
IgA
Interferon