Renal week 3 Flashcards
What do the kidneys do
Make urine Regulate Na Regulate fluid balance Acid base - bicarb excretion and reabsorption BP regulation RBC production Converts inactive vitamin D to active form Prostaglandin secretion
Prostaglandin
vasodilate blood vessels ?
What is released by kidneys for RBC production
Erythropoetin
What is healthy UOP
- 5L Q24 hours
- - 30ml/hour
edema build up after 2.5-3L of fluid retained
how much K excreted by kidneys
90%
Gero: kidney
decreased ability to adjust to the changes in H2O / electrolyte
Gero: blood flow
Increased for for failure r/t polypharm., comorbidities, decreased renal function
Gero: tubule system
Loss of ability to conserve / excrete Na and hydrogen
- decline ability to concentrate
- increased risk for dehydration
Gero: nephrons
altered drug excretion and drug-drug interaction
Glomerulernephritis
infection/inflammation of glomerulers
Polycystic kidneys
patient develops cysts which alters form of nephrons
nephrotic syndrome
common in younger patients
high lipids, high amount of edema
Rhabdomylosis
results in muscle damage
clogged nephrons
Pre-renal disease: impaired perfusion (cause)
- cardiac failure
- sepsis
- blood loss
- dehydration
- vascular occlusion
Renal disease: Glomerularnephritis, small vessel vasculitis, acute tubular necrosis (cause?)
- drugs, toxins, prolonged hypotension, interstitial
Renal disease: interstitial nephritis (cause)
drugs, toxins, inflammatory disease, infection
Post renal disease (cause)?
urinary calculi retroperitoneal fibrosis benign prostatic enlargement prostate cancer cervical cancer urethral stricture/valves meatal stenosis/phimosis
kidneys want MAP to be what?
above 65
Acute kindey injury: Oliguric phase (signs and symptoms)
Oliguria (<40mL/day within 1-7 days of kidney injury)
Urinalysis (casts, RBC, WBC, sp gr fixated at 1.010)
Metabolic acidosis
hyperkalemia and hyponatremia
elevated BUN and creatinine
Fatgue / malaise
Acute kidney injury: diuretic phase (s/s)
gradual increase UOP –> 1-3L/day; may reach 3-5
hypovolemia, dehydration
hypotension
BUN and creatinine levels begin to normalize