Renal/Urinary Flashcards
The kidneys receive how much cardiac output?
20-25%
What substances are not supposed to be in urine?
Protein and glucose
Renal threshold for glucose urine..
180 mg/dL
Vasopressin is also known as…
ADH (antidiuretic hormone)
Osmolarity is
ratio of solute to water
Osmolality is
a measurement, the degree of dilution or concentration of the urine.
When the kidneys sense a decrease in blood pressure…
Renin is released, which causes kidneys to hold onto aldosterone, to retain fluids, to increase blood pressure
A primary cause of hypertension…
failure of the renin mechanism.
Renal clearance is..
the ability of the kidneys to clear solutes from the plasma (24 hour urine collection)
Creatinine clearance is..
the best approximation of renal function; a good measure of the GFR. (125)
Normal adult GFR:
125-200 mL/min
If kidney problems are detected (lab changes)
creatinine clearance decreases; serum creatinine increases; BUN increases.
Older patients have how much GFR compared to younger adults?
50%,
Erythropoietin stimulates
bone marrow to produce RBCs, which carry oxygen throughout body.
Normal BUN..
10-20
Normal creatinine..
0.5-1.5
If urea is not sufficiently excreted in the urine…
it accumulates in body tissues
Normal specific gravity..
1.010-1.030
Specific gravity increases when..
fluid intake decreases (concentrated urine)
Specific gravity decreases when..
fluid intake increases (diluted urine)
Serum creatinine does NOT increase until..
at least 50% of the kidney function is lost.
A serum creatinine level of 1.5 or above means…
risk for acute kidney injury from iodinated contrast dyes and some drugs
Nephrotoxic meds must be discontinued how long before contrast urologic testing?
24 hours
Before testing for at risk-patients, you should always check..
kidney function
Contrast-induced kidney failure..
onset of acute kidney failure 24-72 hours after iodine contrast given.
Post contrast, patients taking glucophage (Metformin) are at risk for…
lactic acidosis
Glucophage cannot be given for how long after a contrast procedure?
48 hours
Post biopsy education..
urine may contain blood for 24-48 hours; monitor for S/S of bleeding.
Chronic kidney disease means..
kidney damage or a decrease in the GFR that lasts more than 3 months.
Nephrosclerosis is..
the thickening in the nephron blood vessels (will cause kidneys to shrink and atrophy)
Treatment for nephrosclerosis..
Treat blood pressure (ACE inhibitors)
Acute Nephritic Syndrome..
kidney disease with glomerular inflammation (caused by immune response)
Acute Nephritic Syndrome main sympmtom..
oliguria (<400ml/24h)
Oliguria is..
urine output less than 400 ml in 24 hours
Glomerulonephritis typically occurs…
post infection (may take a couple of weeks)
Complications of glomerulonephritis…
pulmonary edema; heart failure; hypertensive encephalopathy …body is holding onto fluids