Renal Tumors

Question 0

Regular growth pattern and cells free of atypia. Fronds.

Answer 0

Renal papillary adenoma

Question 1

What are the 4 most common benign tumors of the kidney?

Answer 1

Renal papillary adenoma, renal fibroma (hamartoma), angiomyolipoma, oncocytoma

Question 2

Uniform, large polygonal cells; Numerous prominent mitochondria

Answer 2

Oncocytoma

Question 3

What are the 5 primary malignant tumors of the kidney?

Answer 3

Renal cell carcinoma, papillary carcinoma, renal sarcomas, collecting duct tumors, Wilm’s tumor (nephroblastoma)

Question 4

Most common primary renal tumor of childhood

Answer 4

Wilm’s tumor (nephroblastoma)

Question 5

Which chromosome is affected in Wilm’s tumor?

Answer 5

11

Question 7

Large, well circumscribed lesion that is grayish-tan in color

Answer 7

Wilm’s tumor (nephroblastoma)

Question 8

nests of primitive appearing cells that stain deep blue or purple.

Answer 8

Wilm’s tumor

Question 8

What do Wilm’s tumor cells resemble?

Answer 8

the nephrogenic zone of the fetal kidney.

Question 9

Most common type of renal malignancy

Answer 9

Renal cell carcinoma

Question 10

Where do renal cell carcinomas originate?

Answer 10

within the renal cortex

Question 11

responsible for 80 to 85% of all primary renal neoplasms.

Answer 11

Renal cell carcinoma

Question 12

Classic triad of RCC

Answer 12

flank pain, hematuria and palpable abdominal mass.

Question 13

What is the major risk factor for RCCA?

Answer 13

tobacoo

Question 14

5-6% chronic dialysis pts develop

Answer 14

renal cell carcinoma

Question 15

tan to yellow in color in the gross specimen

Answer 15

Renal cell carcinoma

Question 16

What are 5 distinct cell types of renal cell carcinoma?

Answer 16

Clear cell carcinoma, chromophilic carcinoma, chromophobic carcinoma, oncocytic carcinoma, collecting duct carcinoma

Question 17

Most common cell type in RCC?

Answer 17

Clear cell

Question 18

From where do clear cell carcinomas arise?

Answer 18

Proximal tubule

Question 19

also arise from proximal tubule cells and are occasionally referred to as papillary renal carcinomas.

Answer 19

Chromophilic carcinomas

Question 20

originate from cortical collecting dust and are composed of sheets of cells which appear darker then cells of clear cell carcinoma.

Answer 20

chromophobic carcinomas

Question 21

arise from collecting duct cells and consists of large well differentiated neoplastic cells with a characteristic large number of mitochondria

Answer 21

Oncocytomas

Question 22

Classic histolgic features: neoplastic cells that have clear cytoplasm that are arranged in nests with intervening blood vessels.

Answer 22

Renal cell carcinoma

Question 23

Density is greater at the periphery of the tumor cells in which patients?

Answer 23

Chromophobic

Question 24

common sites for mets in RCCA?

Answer 24

lung, lymph nodes, bone, liver, brain, ipsilateral adrenal gland and contralateral kidney.

Question 25

Common cancers with mets to the kidneys

Answer 25

lung, breast, uterus, ovaries, stomach, intestines and pancreas.