Renal tubular reabsorption and secretion Flashcards
Define primary vs secondary active transport
What’s the main function of the proximal tubule?
What’s the main function of the descending loop of Henle?
What’s the main function of the thin ascending loop of Henle?
What’s the main function of the thick ascending loop of Henle?
Where is water most permeable in the Loop of Henle?
Where does thiazide diuretics act on?
Where does furosemide act on?
Where is the location of the ascending/descending loop of Henle?
What’s the water permeability in the early portion of the distal tubule?
What’s the MOA of ADH?
What are the 2 main cell types found in the distal tubules/ collecting duct and their functions?
Urea is reabsorbed by passive diffusion as it follows osmosis of water - how can it still be secreted in urine?
Where is the juxtaglomerular complex located? What’s its function?
Where does K+ sparing diuretics act on?
What are the 2 types of intercalated cells and their functions?
How is the function of the principal cells regulated?
aldosterone
What are the 3 main functions of the medullary collecting duct?
Where do Na+ channel blockers work?
fig 28-12
What are the 2 primary forces that determine the peritubular capillary reabsorption?
What are the 2 determinants of peritubular capillary hydrostatic pressures?
What are the 2 determinants of peritubular capillary oncotic pressures?
How does increased arterial blood pressure influence reabsorption rate (3 main mechanisms)?
How does increased filtration fraction influence reabsorption rate?
H
How does Addison’s effect sodium and potassium levels in the body?
What is the most powerful Na+ retention hormone in the body?
What are the 3 mechanisms of Na+ retention action of Angiotensin II?
What are the 5 hormones that regulate tubular reabsorption?
table 28-3
