Renal syndrome associations Flashcards
Minimal change disease:
A. Homogenous intramembranous deposition replacing the lamina densa in the glomerular basement membranes
B. Mesangial and capillary loop immune complexes
C. Necrotizing or crescentic “pauci-immune” glomerulonephritis
D. Nodular mesangial acellular expansion
E. Peritubular mononuclear inflammatory infiltrate with numerous eosinophils +/- lymphocytic tubulitis
F. Peritubular inflammation with significant neutrophil component and “pus casts”
G. Podocyte foot process fusion (“foot process effacement”) diffusely
H. Subepithelial immune complexes without significant glomerular hypercellularity
I. Thickening, “splitting” and “basket-weaving” of the lamina densa of the glomerular basement membrane
J. Thrombotic microangiopathy
G
Hemolytic uremic syndrome
A. Homogenous intramembranous deposition replacing the lamina densa in the glomerular basement membranes
B. Mesangial and capillary loop immune complexes
C. Necrotizing or crescentic “pauci-immune” glomerulonephritis
D. Nodular mesangial acellular expansion
E. Peritubular mononuclear inflammatory infiltrate with numerous eosinophils +/- lymphocytic tubulitis
F. Peritubular inflammation with significant neutrophil component and “pus casts”
G. Podocyte foot process fusion (“foot process effacement”) diffusely
H. Subepithelial immune complexes without significant glomerular hypercellularity
I. Thickening, “splitting” and “basket-weaving” of the lamina densa of the glomerular basement membrane
J. Thrombotic microangiopathy
J
Malignant hypertension
A. Homogenous intramembranous deposition replacing the lamina densa in the glomerular basement membranes
B. Mesangial and capillary loop immune complexes
C. Necrotizing or crescentic “pauci-immune” glomerulonephritis
D. Nodular mesangial acellular expansion
E. Peritubular mononuclear inflammatory infiltrate with numerous eosinophils +/- lymphocytic tubulitis
F. Peritubular inflammation with significant neutrophil component and “pus casts”
G. Podocyte foot process fusion (“foot process effacement”) diffusely
H. Subepithelial immune complexes without significant glomerular hypercellularity
I. Thickening, “splitting” and “basket-weaving” of the lamina densa of the glomerular basement membrane
J. Thrombotic microangiopathy
J
Dense Deposit Disease (aka membranoproliferative glomerulonephritis type II)
A. Homogenous intramembranous deposition replacing the lamina densa in the glomerular basement membranes
B. Mesangial and capillary loop immune complexes
C. Necrotizing or crescentic “pauci-immune” glomerulonephritis
D. Nodular mesangial acellular expansion
E. Peritubular mononuclear inflammatory infiltrate with numerous eosinophils +/- lymphocytic tubulitis
F. Peritubular inflammation with significant neutrophil component and “pus casts”
G. Podocyte foot process fusion (“foot process effacement”) diffusely
H. Subepithelial immune complexes without significant glomerular hypercellularity
I. Thickening, “splitting” and “basket-weaving” of the lamina densa of the glomerular basement membrane
J. Thrombotic microangiopathy
A
Primary membranous nephropathy
A. Homogenous intramembranous deposition replacing the lamina densa in the glomerular basement membranes
B. Mesangial and capillary loop immune complexes
C. Necrotizing or crescentic “pauci-immune” glomerulonephritis
D. Nodular mesangial acellular expansion
E. Peritubular mononuclear inflammatory infiltrate with numerous eosinophils +/- lymphocytic tubulitis
F. Peritubular inflammation with significant neutrophil component and “pus casts”
G. Podocyte foot process fusion (“foot process effacement”) diffusely
H. Subepithelial immune complexes without significant glomerular hypercellularity
I. Thickening, “splitting” and “basket-weaving” of the lamina densa of the glomerular basement membrane
J. Thrombotic microangiopathy
H
Acute pyelonephritis
A. Homogenous intramembranous deposition replacing the lamina densa in the glomerular basement membranes
B. Mesangial and capillary loop immune complexes
C. Necrotizing or crescentic “pauci-immune” glomerulonephritis
D. Nodular mesangial acellular expansion
E. Peritubular mononuclear inflammatory infiltrate with numerous eosinophils +/- lymphocytic tubulitis
F. Peritubular inflammation with significant neutrophil component and “pus casts”
G. Podocyte foot process fusion (“foot process effacement”) diffusely
H. Subepithelial immune complexes without significant glomerular hypercellularity
I. Thickening, “splitting” and “basket-weaving” of the lamina densa of the glomerular basement membrane
J. Thrombotic microangiopathy
F
Amyloid nephropathy
A. Homogenous intramembranous deposition replacing the lamina densa in the glomerular basement membranes
B. Mesangial and capillary loop immune complexes
C. Necrotizing or crescentic “pauci-immune” glomerulonephritis
D. Nodular mesangial acellular expansion
E. Peritubular mononuclear inflammatory infiltrate with numerous eosinophils +/- lymphocytic tubulitis
F. Peritubular inflammation with significant neutrophil component and “pus casts”
G. Podocyte foot process fusion (“foot process effacement”) diffusely
H. Subepithelial immune complexes without significant glomerular hypercellularity
I. Thickening, “splitting” and “basket-weaving” of the lamina densa of the glomerular basement membrane
J. Thrombotic microangiopathy
D
Alport syndrome
A. Homogenous intramembranous deposition replacing the lamina densa in the glomerular basement membranes
B. Mesangial and capillary loop immune complexes
C. Necrotizing or crescentic “pauci-immune” glomerulonephritis
D. Nodular mesangial acellular expansion
E. Peritubular mononuclear inflammatory infiltrate with numerous eosinophils +/- lymphocytic tubulitis
F. Peritubular inflammation with significant neutrophil component and “pus casts”
G. Podocyte foot process fusion (“foot process effacement”) diffusely
H. Subepithelial immune complexes without significant glomerular hypercellularity
I. Thickening, “splitting” and “basket-weaving” of the lamina densa of the glomerular basement membrane
J. Thrombotic microangiopathy
I
Diabetic nephropathy
A. Homogenous intramembranous deposition replacing the lamina densa in the glomerular basement membranes
B. Mesangial and capillary loop immune complexes
C. Necrotizing or crescentic “pauci-immune” glomerulonephritis
D. Nodular mesangial acellular expansion
E. Peritubular mononuclear inflammatory infiltrate with numerous eosinophils +/- lymphocytic tubulitis
F. Peritubular inflammation with significant neutrophil component and “pus casts”
G. Podocyte foot process fusion (“foot process effacement”) diffusely
H. Subepithelial immune complexes without significant glomerular hypercellularity
I. Thickening, “splitting” and “basket-weaving” of the lamina densa of the glomerular basement membrane
J. Thrombotic microangiopathy
D
Allergic interstitial nephritis
A. Homogenous intramembranous deposition replacing the lamina densa in the glomerular basement membranes
B. Mesangial and capillary loop immune complexes
C. Necrotizing or crescentic “pauci-immune” glomerulonephritis
D. Nodular mesangial acellular expansion
E. Peritubular mononuclear inflammatory infiltrate with numerous eosinophils +/- lymphocytic tubulitis
F. Peritubular inflammation with significant neutrophil component and “pus casts”
G. Podocyte foot process fusion (“foot process effacement”) diffusely
H. Subepithelial immune complexes without significant glomerular hypercellularity
I. Thickening, “splitting” and “basket-weaving” of the lamina densa of the glomerular basement membrane
J. Thrombotic microangiopathy
E
Primary focal and segmental glomerulosclerosis
A. Homogenous intramembranous deposition replacing the lamina densa in the glomerular basement membranes
B. Mesangial and capillary loop immune complexes
C. Necrotizing or crescentic “pauci-immune” glomerulonephritis
D. Nodular mesangial acellular expansion
E. Peritubular mononuclear inflammatory infiltrate with numerous eosinophils +/- lymphocytic tubulitis
F. Peritubular inflammation with significant neutrophil component and “pus casts”
G. Podocyte foot process fusion (“foot process effacement”) diffusely
H. Subepithelial immune complexes without significant glomerular hypercellularity
I. Thickening, “splitting” and “basket-weaving” of the lamina densa of the glomerular basement membrane
J. Thrombotic microangiopathy
G
Scleroderma crisis
A. Homogenous intramembranous deposition replacing the lamina densa in the glomerular basement membranes
B. Mesangial and capillary loop immune complexes
C. Necrotizing or crescentic “pauci-immune” glomerulonephritis
D. Nodular mesangial acellular expansion
E. Peritubular mononuclear inflammatory infiltrate with numerous eosinophils +/- lymphocytic tubulitis
F. Peritubular inflammation with significant neutrophil component and “pus casts”
G. Podocyte foot process fusion (“foot process effacement”) diffusely
H. Subepithelial immune complexes without significant glomerular hypercellularity
I. Thickening, “splitting” and “basket-weaving” of the lamina densa of the glomerular basement membrane
J. Thrombotic microangiopathy
J
IgA nephropathy
A. Homogenous intramembranous deposition replacing the lamina densa in the glomerular basement membranes
B. Mesangial and capillary loop immune complexes
C. Necrotizing or crescentic “pauci-immune” glomerulonephritis
D. Nodular mesangial acellular expansion
E. Peritubular mononuclear inflammatory infiltrate with numerous eosinophils +/- lymphocytic tubulitis
F. Peritubular inflammation with significant neutrophil component and “pus casts”
G. Podocyte foot process fusion (“foot process effacement”) diffusely
H. Subepithelial immune complexes without significant glomerular hypercellularity
I. Thickening, “splitting” and “basket-weaving” of the lamina densa of the glomerular basement membrane
J. Thrombotic microangiopathy
B
Granulomatosis with polyangiitis
A. Homogenous intramembranous deposition replacing the lamina densa in the glomerular basement membranes
B. Mesangial and capillary loop immune complexes
C. Necrotizing or crescentic “pauci-immune” glomerulonephritis
D. Nodular mesangial acellular expansion
E. Peritubular mononuclear inflammatory infiltrate with numerous eosinophils +/- lymphocytic tubulitis
F. Peritubular inflammation with significant neutrophil component and “pus casts”
G. Podocyte foot process fusion (“foot process effacement”) diffusely
H. Subepithelial immune complexes without significant glomerular hypercellularity
I. Thickening, “splitting” and “basket-weaving” of the lamina densa of the glomerular basement membrane
J. Thrombotic microangiopathy
C
Class IV Diffuse proliferative Lupus nephritis
A. Homogenous intramembranous deposition replacing the lamina densa in the glomerular basement membranes
B. Mesangial and capillary loop immune complexes
C. Necrotizing or crescentic “pauci-immune” glomerulonephritis
D. Nodular mesangial acellular expansion
E. Peritubular mononuclear inflammatory infiltrate with numerous eosinophils +/- lymphocytic tubulitis
F. Peritubular inflammation with significant neutrophil component and “pus casts”
G. Podocyte foot process fusion (“foot process effacement”) diffusely
H. Subepithelial immune complexes without significant glomerular hypercellularity
I. Thickening, “splitting” and “basket-weaving” of the lamina densa of the glomerular basement membrane
J. Thrombotic microangiopathy
B
