Renal Replacement Therapy Flashcards

1
Q

What are the renal functions

A

excretory function
water and electrolyte balance
acid base balance
renal endocrine function

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2
Q

What are the renal endocrine functions

A

erythropoietin
calcium metabolism
renin secretion

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3
Q

Is renal dialysis an active or passive process

A

Passive

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4
Q

How is renal dialysis passive

A

it is diffusion across concentration gradients

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5
Q

What does renal dialysis allow

A

intermittent correction of changes in plasma concentration of small molecules

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6
Q

What are the 2 types of renal dialysis

A

haemodialysis

peritoneal dialysis

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7
Q

What is hemodialysis

A

blood taken to outside the body, filtered and returned

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8
Q

What is peritoneal dialysis

A

inside the body

utilizes the inside layers of the peritoneum which has an exposed layer of BV

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9
Q

What happens in dialysis

A

There are holes which are not big enough to allow RBC and proteins through but allows electrolyte exchange

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10
Q

How do you allow for dialysis to be a passive process

A

The solution put in the machine should be what you want in the blood
You need to make a concentration gradient

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11
Q

What is the heparin pump for

A

Stop blood clotting in machine

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12
Q

What happens in peritoneal dialysis

A

The fluid is pumped into the peritoneal space

exchange occurs and the fluid and waste products are drained from the peritoneal space

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13
Q

What does peritoneal dialysis allow for

A

Much more flexibility

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14
Q

How is erythropoietin replaced

A

by EPO injections

maintains red cell mass

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15
Q

How is bone mass maintenance replaced

A

Vitamin D supplementation

osteoporosis prevention programme

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16
Q

How can hypertension control be an issue in renal disease

A

the renin angiotensin system is inactive

ace inhibitors may have limited use

17
Q

What is the optimal treatment for ESRD

A

renal transplantation

18
Q

Why is renal transplantation the optimal Tx

A

normal renal function is there
no dietary restrictions
normal energy and fertility

19
Q

Who has priority for renal transplants

A

children

20
Q

Are kidneys removed in a transplant

A

No
new kidney is placed in pelvis
it is vulnerable in contact sports

21
Q

What are the transplant problems

A

rejection
immunosuppression
high cardiovascular mortality
osteoporosis risk

22
Q

Why is there transplant rejection

A

the immune system treats it as foreign and attacks it

23
Q

Why is there immunosuppression in transplant

A

Due to medications taken to stop rejection

reduce the immune system reaction overall

24
Q

What is a transplant patient who is immunosuppressed at risk of

A

increased infection risk

malignancy risk

25
Q

Which donor is better - deceased or live

A

live

26
Q

When should patients with dialysis be dental treated

A

after hemodialysis sessions (this is not necessary with PD patients)

27
Q

When prescribing drugs to renal diseased patients what should you do

A

lease with physician

28
Q

Why should you be wary of the arm

A

this is where dialysis takes place

infection of the arm means dialysis cannot occur

29
Q

How does renal transplant effect dentistry

A

kidney function will drop over time

there may be immunsupression - risk of infection and cancer

30
Q

What are the drugs that those with a renal transplant may be on

A
prednisolone 
azathioprine
tacrolimus
cyclosporin 
may be prone to drug interactions
31
Q

What should you be aware of regarding renal transplant patients and their drugs

A

they could have steroid side effects

32
Q

Why should you be more suspicious of oral mucosal lesions in renal transplant patients

A

they have an increased cancer risk