renal part 3 (obstructive disorders) Flashcards

1
Q

obst. disorders are classified by what three things?

A

classified according to site, degree (complete or partial), and duration of obstruction (acute or chronic)

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2
Q

lower urinary tract vs upper urinary tract obst. disorders: where are they located? bilateral or unilateral?

A

Lower urinary tract obstructions are located below the UVJ and are bilateral.

Upper urinary tract obstructions are located above the UVJ and are usually unilateral.

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3
Q

higher or lower level of obstruction worse? why?

A

higher :

  • stasis of urine (which predisposes to infx and stone formation)
  • progressive dilation of the renal collecting ducts and renal tubular structures, which causes destruction and atrophy of renal tissue
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4
Q

level of obst: renal pelvis

what is the cause?

A

Renal calculi or papillary necrosis

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5
Q

level of obst: ureter

what is the cause?

A

Renal calculi, pregnancy, tumors that compress the ureter, ureteral stricture, congenital d/o of the UVJ and UVJ strictures

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6
Q

level of obst:bladder and urethera

what is the cause?

A

Bladder CA, neurogenic bladder, bladder stones, prostatic hyperplasia or CA, urethral strictures, congenital urethral defects

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7
Q

hydronephrosis: urine-filled dilation of the ______and _____ associated with …

A

urine-filled dilation of the renal pelvis and calyces associated with progressive atrophy of the kidney d/t obstruction or urine outflow

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8
Q

hydronephrosis: clinical features of urinary obst: depend on ___, ____ and ____. symptoms reflect what?

A

depend on the site of obstruction, cause, and the rapidity with which the condition developed; sx will reflect the underlying process

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9
Q

nephrolithiasis: kidney stones: forms because of …. what can it cause?

A

supersaturated urine and an environment that allows the stone to grow
Can cause intrinsic and/or post-renal failure (esp. when they become ureterolithiasis)

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10
Q

what is the most common cause of upper urinary tract obstruction?

A

kidney stone

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11
Q

clinical features of kidney stones: two types

A

renal colic (more common) or noncolic renal pain

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12
Q

kidney stones: renal colic: due to what? what is the pain like? location?

A

d/t stretching of the collecting system or ureter;
intermittent,unlilateral flank pain
may radiate into groin/scrotum, N/V

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13
Q

what is non-colicky renal pain? causes, what is the pain like? what makes it worse?

A

caused by distention of the renal calyces or renal pelvis; dull, deep ache in the flank or back
worse with drinking water,

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14
Q

txt of kidney stones

A

pain meds

flomax (to dilate ureters)

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15
Q

what is the most common abd tumor in children? what is is assosciated with?

A

wilms tumor - a malignant tumor of kidney

assosciated with aniridia (absence of the iris)

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16
Q

3 types of malignant kidney tumors?

A

wilms tumor
renal cell carcinoma
bladder cancer

17
Q

which accounts for 95% of kindey tumors?

A

renal cell carcinoma - located on cortex, common in obese women and smokers

18
Q

what may be a cause of painless hematuria?

A

bladder cancer

19
Q

most common type of bladder cancer?

A

Urothelial carcinoma, also known as transitional cell carcinoma (TCC)

20
Q

UA finding: WBC casts

what is the renal condition?

A

pyelonephritis

21
Q

UA finding: pigmented granular casts, myoglobin positive, dark/red/coco-cola urine
what is the renal condition?

A

rhabdomyalosis

22
Q

UA finding: Red cell casts

what is the renal condition?

A

acute glomerulonephritis

23
Q

UA finding: White cell casts + eiosinophils

what is the renal condition?

A

acute interstitial nephritis

24
Q

UA finding: muddy brown casts

what is the renal condition?

A

acute tubular necrosis

25
Q

UA finding: normal or hyaline casts

what is the renal condition?

A

pre-renal azotemia

26
Q

UA finding: broad waxy casts

what is the renal condition?

A

chronic renal failure

27
Q

UA finding: Tea colored urine, hematuria
RBC casts, protein <3.5 g/day
what is the renal condition?

A

nephritic syndrome

28
Q

UA finding:Protein >3.5 g/day, oval fat bodies,
Free fat, fatty casts
what is the renal condition?

A

nephrotic syndrome

29
Q

uncomplicated pyelonephritis: what is the initial and step down therapy for inpatient? how many days of each?

A

initial: ceftriaxone 1g IV every 24hr
(at least one dose IV, change to PO when able)
step-down: cephalexin (keflex) 500 mg PO BID
BOTH: 10-14 days

30
Q

what to remember about step-down txt for pyelonephritis in-pt?

A

keflex 500mg PO BID

requires renal dose adjustment

31
Q

what lab do you NEED for uncomplicated pyelonephritis?

A

CULTURE - then txt…