Renal Labs Flashcards

1
Q

What is included within a UA

A

RBCs, nitrites, WBC esterase by dipstick

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2
Q

What is measured with a UA

What type of test is this

A

pH, specific gravity, protein, glucose

Macroscopic

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3
Q

What is looked for in the analysis of urine

What type of test is this

A

casts, crystals, and cells (sediment)

Microscopic

requires a lab

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4
Q

what is required by the patient for a good UA sample

A

Needs to be tested w/n 2 hours
mid-stream CLEAN catch

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5
Q

What is the pathologic cause of cloudy urine

food/drug cause?

A

Pyuria
Lipiduria

Purine-rich foods

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6
Q

What is the pathologic cause for dark yellow urine

Food/drug cause

A

Concentrated urine

Carrots

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7
Q

What is the pathologic cause of orange urine

Food/drug cause?

A

Bile

phenothiazines, pyridium

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8
Q

What is the pathologic cause of red urine

food/drug cause

A

hamturia
hemoglobinuria
myoglobinuria

rifampin, beets, blackberries, rhubarb

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9
Q

What is the pathologic cause of brown urine

food/drug cause

A

Bile
myoglobin

fava beans, flagyl, L-dopa, nitrofuritonin

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10
Q

What is the pathologic cause of green/blue urine

food/drug?

purple bag syndrome

A

Multiple bacteria (indwelling catheter)

amitriptyline, IV cimetidine

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11
Q

What is the marker for the presence of RBC in urine

A

Leukocyte esterase

negative to +3

not an actual number

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12
Q

What test correlates with urine osmolality

what if its high?

What if its low?

A

Specific gravity

AKI, DI, overhydration

SIADH, addisons, dehydration

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13
Q

What will cause the urine to be alkalotic

A

Staghorn, Citrate foods

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14
Q

What is the normal pH of urine

A

5.5 to 6.5

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15
Q

What issue will cause a false positive for blood in urine test

A

Rhabdomyolysis

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16
Q

Is Billirubin present in urine in healthy people?

A

no

but small amounts of Urobilinogen will be present

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17
Q

If Ketones come back high with a dipstick test, what should your next step be

A

getting a serum ketone level

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18
Q

What is the most abundant Ketone with DKA and AKA

A

Beta-Hydroxybutyric acid

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19
Q

What needs to be added to a a dipstick urine sample when looking for albumin

What is a normal albumin excretion level

A

Bromphenol blue

<30

20
Q

What is the screening test of choice for diabetic neuropathy

A

Urine albumin to creatinine ratio

*requires a 24hr collection

21
Q

What is a normal 24 hour urine output amount

A

800-2000mL/day

22
Q

What can renal tubular cells progress to

What are they indicative of

A

oval fat bodies

suggests pathology

23
Q

What are casts

A

Cylindrical structures composed of mucoprotein

24
Q

What are the different types of casts that can be present in urine

A

Hyaline
waxy
RBC/WBC
epithelial
granular
muddy brown
fatty
mixed

25
What type of casts indicate advanced/chronic renal disease
waxy/broad cats
26
What causes RBC casts
glomerulonephritis
27
What casts will be seen with kidney inflammation or infection
WBC casts
28
What type of casts does intense exercise/ dehydration, ESRD cause
Granular *Muddy brown casts
29
What type of casts are pathognomonic for acute tubular necrosis (ATN)
Muddy brown casts
30
What is the most common cause of kidney stones
Calcium oxalate
31
What is struvite | how are the crystals described
magnesium-ammonium-phosphate | coffin lid crystals
32
Which medications can lead to renal crystal formation
Acyclovir Sulfa drugs Atazanavir methotrexate
33
What is the most common urine culture medium (sensitivity)
blood agar MacConkey agar
34
What urine test is best for the workup of hypo/hypernatremia, SIADH, and DI
osmolality
35
Is a urine Hcg test quantitative or qualitative
Qualitative
36
What is the waste product from liver metabolism of protein called | What does this test for
Nitrogen | function of renal and liver function
37
What is a normal BUN
8-18mg/dL
38
What factors will decrease your BUN
low protein diet malnutrition severe liver damage
39
What is the best measure of Kidney function and why
Creatinine which is a marker for GFR | creatinine is almost completely excreted by the kidneys
40
What is a normal creatinine
.6-1.2
41
What are some important factors when creatinine is measured
pts. muscle mass needs to be accounted for small rise at the lower end of the scale can mean a BIG decrease in GFR
42
What causes a decrease in creatinine
pregnancy starvation wasting disease corticosteroids dialysis
43
What is a normal BUN/creatinine ration
10:1
44
what is 20:1 BUN/creatinine ratio suggest
pre-renal azotemia -dehydration -renal hypoperfusion
45
What does BUN/creatinine ratio help determine
the casue of AKI or kidney failure
46
What is a noraml eGFR | What is it used for
>90ml/min | used to stage kidney function
47
what eGFR will require dialysis
<15