Renal Failure & Kidney Disorders Flashcards
What is Acute Kidney Injury (AKI)?
Previously known as Acute Renal Failure; Abrupt, often reversible, damage that causes a buildup of waste, fluid, & electrolyte imbalances.
SUDDEN RENAL DAMAGE
What is Prerenal Failure?
Damage BEFORE the kidneys & DECREASED VOLUME/PERFUSION TO THE KIDNEYS.
Causes of Prerenal Failure?
Cardiac damage, decreased or impaired cardiac output (MI), vasodilation, hemorrhage (hypovolemia), burns, GI losses (vomiting/diarrhea).
What is Intrarenal Failure?
Damage IN the kidneys due to PROLONGED ISCHEMIA.
Causes of Intrarenal Failure?
Myoglobinuria, hemoglobinuria, rhabdomyolysis, nephrotoxic drugs (e.g., NSAIDs, antibiotics, chemo drugs, contrast dyes), infections (e.g., glomerulonephritis), or reduced blood supply
What is Postrenal Failure?
Damage AFTER the kidneys due to OBSTRUCTION/BLOCKAGE IN THE URINARY TRACT.
Causes of Postrenal Failure?
Renal calculi (stones), blood clots, retroperitoneal issues, benign prostatic hyperplasia (BPH), tumors, neurological damage (stroke).
What are the phases of AKI?
-Onset phase
-Oliguric (anuric) phase
-Diuretic phase
-Recovery phase
Memory aid: ‘OH OH DARN RENAL’.
What is the Oliguric phase (2nd phase)?
Time frame: 1-7 days
Description: Glomerulus decreases the ability to filter blood = decrease urine output
Treatment: Strict I&Os, daily weight, dialysis may be needed until kidney function returns, Monitor EKG & labs (watch for hyperkalemia), low-protein diet, limited fluid intake
What is the Diuretic phase (3rd phase)?
Time frame: 1-3 weeks.
Description: Cause of AKI is corrected, gradual increase in urinary output (large amount of diluted urine with electrolytes)
Treatment: Monitor for dehydration & hypokalemia
What is the Recovery phase (final)?
Time frame: 3-12 months.
Description: increase in kidney function
Treatment: some develop chronic kidney disease (CKD)
Needs dialysis or kidney transplant
What is the treatment for AKI?
Treat the underlying cause to prevent long-term damage.
What diet modifications are needed for AKI?
Low-protein diet and limited fluid intake.
What should be monitored in patients with AKI?
Monitor for dehydration & hypokalemia (K+ < 3.5).
What treatments may be needed for AKI?
Dialysis and kidney transplant may be required.
What is Acute Glomerulonephritis (AGM) also referred to as?
Post-streptococcal glomerulonephritis
What triggers inflammation in Acute Glomerulonephritis?
Formation of antigen-antibody complexes resulting from strep trigger inflammation
How long after a streptococcal infection do antibodies get lodged in the glomeruli?
14 days after infection
What are the signs and symptoms of Acute Glomerulonephritis?
Hypertension, Positive ASO test results, Swelling in the face/eyes,
Tea-colored urine (due to a toe is: build up of waste products),
Recent strep infection, Decreased GFR,
Elevated labs: increased BUN & creatinine levels, mild Proteinuria
What is the treatment for Acute Glomerulonephritis?
Medications:
Antibiotics, Antihypertensives, Diuretics, Corticosteroids
Monitor fluid status:
Strict I&Os, assess urine color, daily weights (best indicator), assess for edema, auscultate hear & lung sounds (abnormal can indication fluid)
Diet:
Fluid & sodium restriction
-decreased protein
-increase carbs (as they provide energy & stop the breakdown of protein)
What can abnormal lung sounds indicate in patients with Acute Glomerulonephritis?
Presence of fluid in the lungs
What is Chronic Kidney Disease (CKD)?
CKD is a gradual and irreversible loss of kidney function that occurs over a long period of time.
What are the stages of CKD based on?
The stages of CKD are based on the glomerular filtration rate (GFR).
What are the GFR ranges for CKD stages?
> 90: Stage 1
60-89: Stage 2
45-59: Stage 3A
30-44: Stage 3B
15-29: Stage 4
< 15: End-stage renal disease (ESRD)